plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:1

A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies A Functionally Conserved Gene Regulatory Network Module Governing Olfactory Neuron Diversity A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair A Novel,Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development A Spatial Framework for Understanding Population Structure and Admixture A trans-acting Variant within the Transcription Factor RIM101 Interacts with Genetic Background to Determine its Regulatory Capacity Adaptive Protein Evolution in Animals and the Effective Population Size Hypothesis Arabidopsis ERF1 Mediates Cross-Talk between Ethylene and Auxin Biosynthesis during Primary Root Elongation by Regulating ASA1 Expression Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei CFLAP1 and CFLAP2 Are Two bHLH Transcription Factors Participating in Synergistic Regulation of AtCFL1-Mediated Cuticle Development in Arabidopsis Chromosomal Integrity after UV Irradiation Requires FANCD2-Mediated Repair of Double Strand Breaks Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent,microRNA-Assisted MCM2-7 Downregulation Consent Codes: Upholding Standard Data Use Conditions Dynamic Sumoylation of a Conserved Transcription Corepressor Prevents Persistent Inclusion Formation during Hyperosmotic Stress ECM-Regulator timp Is Required for Stem Cell Niche Organization and Cyst Production in the Drosophila Ovary Erratum: Correction: Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities (PLoS genetics (2015) 11 12 (e1005745)) - صفحه:e1005832- Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation Genetic Variation,Not Cell Type of Origin,Underlies the Majority of Identifiable Regulatory Differences in iPSCs Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia H-NS Facilitates Sequence Diversification of Horizontally Transferred DNAs during Their Integration in Host Chromosomes Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors Innovation of a Regulatory Mechanism Modulating Semi-determinate Stem Growth through Artificial Selection in Soybean Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila P1 Ref Endonuclease: A Molecular Mechanism for Phage-Enhanced Antibiotic Lethality PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7 Preferential Allele Expression Analysis Identifies Shared Germline and Somatic Driver Genes in Advanced Ovarian Cancer Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation Quantitative Genetics Identifies Cryptic Genetic Variation Involved in the Paternal Regulation of Seed Development RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells SLO BK Potassium Channels Couple Gap Junctions to Inhibition of Calcium Signaling in Olfactory Neuron Diversification Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish Socs36E Controls Niche Competition by Repressing MAPK Signaling in the Drosophila Testis Specific Hsp100 Chaperones Determine the Fate of the First Enzyme of the Plastidial Isoprenoid Pathway for Either Refolding or Degradation by the Stromal Clp Protease in Arabidopsis Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility The Drosophila Helicase MLE Targets Hairpin Structures in Genomic Transcripts The LSH/DDM1 Homolog MUS-30 Is Required for Genome Stability,but Not for DNA Methylation in Neurospora crassa The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability TrpA1 Regulates Defecation of Food-Borne Pathogens under the Control of the Duox Pathway Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila