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The SnRK2 kinases modulate miRNA accumulation in Arabidopsis
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نویسنده
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yan j. ,wang p. ,wang b. ,hsu c.-c. ,tang k. ,zhang h. ,hou y.-j. ,zhao y. ,wang q. ,zhao c. ,zhu x. ,tao w.a. ,li j. ,zhu j.-k.
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منبع
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plos genetics - 2017 - دوره : 13 - شماره : 4
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چکیده
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Micrornas (mirnas) regulate gene expression and play critical roles in growth and development as well as stress responses in eukaryotes. mirna biogenesis in plants requires a processing complex that consists of the core components dicer-like 1 (dcl1),serrate (se) and hyponastic leaves (hyl1). here we show that inactivation of functionally redundant members of the snrk2 kinases,which are the core components of abscisic acid (aba) and osmotic stress signaling pathways,leads to reduction in mirna accumulation under stress conditions. further analysis revealed that the steady state level of hyl1 protein in plants under osmotic stress is dependent on the snrk2 kinases. additionally,our results suggest that the snrk2 kinases physically associate with the mirna processing components se and hyl1 and can phosphorylate these proteins in vitro. these findings reveal an important role for the snrk2 kinases in the regulation of mirna accumulation and establish a mechanism by which aba and osmotic stress signaling is linked to mirna biogenesis. © 2017 yan et al.
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آدرس
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shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, departments of biochemistry,purdue university,west lafayette,in, United States, department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, department of horticulture and landscape architecture,purdue university,west lafayette,in,united states,state key laboratory of wheat and maize crop sciences,college of life science,henan agricultural university,zhengzhou, China, department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, department of horticulture and landscape architecture,purdue university,west lafayette,in,united states,college of biosciences and biotechnology,hunan agricultural university,changsha, China, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States, departments of biochemistry,purdue university,west lafayette,in, United States, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai, China, shanghai center for plant stress biology,and center for excellence in molecular plant sciences,chinese academy of sciences,shanghai,china,department of horticulture and landscape architecture,purdue university,west lafayette,in, United States
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Authors
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