plos genetics سال:2014 - دوره:10

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plos genetics
سال:2014 - دوره:10 - شماره:3

A Combination of Activation and Repression by a Colinear Hox Code Controls Forelimb-Restricted Expression of Tbx5 and Reveals Hox Protein Specificity A Multi-Trait,Meta-analysis for Detecting Pleiotropic Polymorphisms for Stature,Fatness and Reproduction in Beef Cattle ABCC5,a Gene That Influences the Anterior Chamber Depth,Is Associated with Primary Angle Closure Glaucoma An ER Complex of ODR-4 and ODR-8/Ufm1 Specific Protease 2 Promotes GPCR Maturation by a Ufm1-Independent Mechanism An Epigenetic Signature in Peripheral Blood Associated with the Haplotype on 17q21.31,a Risk Factor for Neurodegenerative Tauopathy An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection An Insulin-to-Insulin Regulatory Network Orchestrates Phenotypic Specificity in Development and Physiology An Interspecific Fungal Hybrid Reveals Cross-Kingdom Rules for Allopolyploid Gene Expression Patterns Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer Bacterial Regulon Evolution: Distinct Responses and Roles for the Identical OmpR Proteins of Salmonella Typhimurium and Escherichia coli in the Acid Stress Response CDKN2D-WDFY2 Is a Cancer-Specific Fusion Gene Recurrent in High-Grade Serous Ovarian Carcinoma CDP-Diacylglycerol Synthetase Coordinates Cell Growth and Fat Storage through Phosphatidylinositol Metabolism and the Insulin Pathway CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes Changes in Colorectal Carcinoma Genomes under Anti-EGFR Therapy Identified by Whole-Genome Plasma DNA Sequencing Chromatin Targeting Signals,Nucleosome Positioning Mechanism and Non-Coding RNA-Mediated Regulation of the Chromatin Remodeling Complex NoRC Cleavage Factor I Links Transcription Termination to DNA Damage Response and Genome Integrity Maintenance in Saccharomyces cerevisiae Co-translational Localization of an LTR-Retrotransposon RNA to the Endoplasmic Reticulum Nucleates Virus-Like Particle Assembly Sites Comparative Genomic Analysis of N2-Fixing and Non-N2-Fixing Paenibacillus spp.: Organization,Evolution and Expression of the Nitrogen Fixation Genes Coronary Heart Disease-Associated Variation in TCF21 Disrupts a miR-224 Binding Site and miRNA-Mediated Regulation Correction: A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology Correction: The Genetic Correlation between Height and IQ: Shared Genes or Assortative Mating? DNA Dynamics during Early Double-Strand Break Processing Revealed by Non-Intrusive Imaging of Living Cells DUF1220 Dosage Is Linearly Associated with Increasing Severity of the Three Primary Symptoms of Autism DWARF TILLER1,a WUSCHEL-Related Homeobox Transcription Factor,Is Required for Tiller Growth in Rice Determinants beyond Both Complementarity and Cleavage Govern MicroR159 Efficacy in Arabidopsis Drosophila Pheromone-Sensing Neurons Expressing the ppk25 Ion Channel Subunit Stimulate Male Courtship and Female Receptivity Dying Cells Protect Survivors from Radiation-Induced Cell Death in Drosophila Dysregulated Estrogen Receptor Signaling in the Hypothalamic-Pituitary-Ovarian Axis Leads to Ovarian Epithelial Tumorigenesis in Mice Epigenetic Control of Effector Gene Expression in the Plant Pathogenic Fungus Leptosphaeria maculans FAK Acts as a Suppressor of RTK-MAP Kinase Signalling in Drosophila melanogaster Epithelia and Human Cancer Cells Final Pre-40S Maturation Depends on the Functional Integrity of the 60S Subunit Ribosomal Protein L3 Functional Organization of a Multimodular Bacterial Chemosensory Apparatus GC-Rich DNA Elements Enable Replication Origin Activity in the Methylotrophic Yeast Pichia pastoris Gene-Based Sequencing Identifies Lipid-Influencing Variants with Ethnicity-Specific Effects in African Americans Genetic Basis of Metabolome Variation in Yeast Genetic Determinants Influencing Human Serum Metabolome among African Americans Genetic Dissection of Photoreceptor Subtype Specification by the Drosophila melanogaster Zinc Finger Proteins Elbow and No ocelli Genetic Diversity in the Interference Selection Limit Genome-Wide Analysis of SREBP1 Activity around the Clock Reveals Its Combined Dependency on Nutrient and Circadian Signals Genome-Wide DNA Methylation Analysis Predicts an Epigenetic Switch for GATA Factor Expression in Endometriosis Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke Genomic View of Bipolar Disorder Revealed by Whole Genome Sequencing in a Genetic Isolate Heterozygous De Novo and Inherited Mutations in the Smooth Muscle Actin (ACTG2) Gene Underlie Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome Identification of Interphase Functions for the NIMA Kinase Involving Microtubules and the ESCRT Pathway Integrating Multiple Genomic Data to Predict Disease-Causing Nonsynonymous Single Nucleotide Variants in Exome Sequencing Studies LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection Local Evolution of Seed Flotation in Arabidopsis Lsd1 Restricts the Number of Germline Stem Cells by Regulating Multiple Targets in Escort Cells Mitogen-Activated Protein Kinase (MAPK) Pathway Regulates Branching by Remodeling Epithelial Cell Adhesion Modeling 3D Facial Shape from DNA Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling Parent-of-Origin Effects Implicate Epigenetic Regulation of Experimental Autoimmune Encephalomyelitis and Identify Imprinted Dlk1 as a Novel Risk Gene Photoactivated UVR8-COP1 Module Determines Photomorphogenic UV-B Signaling Output in Arabidopsis RBPJ,the Major Transcriptional Effector of Notch Signaling,Remains Associated with Chromatin throughout Mitosis,Suggesting a Role in Mitotic Bookmarking Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium Sex Chromosome Turnover Contributes to Genomic Divergence between Incipient Stickleback Species Sugar and Chromosome Stability: Clastogenic Effects of Sugars in Vitamin B6-Deficient Cells Suicidal Autointegration of Sleeping Beauty and piggyBac Transposons in Eukaryotic Cells TBX3 Regulates Splicing In Vivo: A Novel Molecular Mechanism for Ulnar-Mammary Syndrome Telomere Shortening Unrelated to Smoking,Body Weight,Physical Activity,and Alcohol Intake: 4,576 General Population Individuals with Repeat Measurements 10 Years Apart Temperate Phages Acquire DNA from Defective Prophages by Relaxed Homologous Recombination: The Role of Rad52-Like Recombinases The ABI4-Induced Arabidopsis ANAC060 Transcription Factor Attenuates ABA Signaling and Renders Seedlings Sugar Insensitive when Present in the Nucleus The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function The First Steps of Adaptation of Escherichia coli to the Gut Are Dominated by Soft Sweeps The Functional Consequences of Variation in Transcription Factor Binding The Hmr and Lhr Hybrid Incompatibility Genes Suppress a Broad Range of Heterochromatic Repeats The Kil Peptide of Bacteriophage λ Blocks Escherichia coli Cytokinesis via ZipA-Dependent Inhibition of FtsZ Assembly The Membrane-Associated Transcription Factor NAC089 Controls ER-Stress-Induced Programmed Cell Death in Plants The Rate of Nonallelic Homologous Recombination in Males Is Highly Variable,Correlated between Monozygotic Twins and Independent of Age The Yeast Sks1p Kinase Signaling Network Regulates Pseudohyphal Growth and Glucose Response The bHLH Factors Extramacrochaetae and Daughterless Control Cell Cycle in Drosophila Imaginal Discs through the Transcriptional Regulation of the cdc25 Phosphatase string Validation and Genotyping of Multiple Human Polymorphic Inversions Mediated by Inverted Repeats Reveals a High Degree of Recurrence Worldwide Patterns of Ancestry,Divergence,and Admixture in Domesticated Cattle