plos genetics سال:2014 - دوره:10

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plos genetics
سال:2014 - دوره:10 - شماره:2

A Cohesin-Independent Role for NIPBL at Promoters Provides Insights in CdLS A Long-Chain Flavodoxin Protects Pseudomonas aeruginosa from Oxidative Stress and Host Bacterial Clearance A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning Analysis of Meiosis in SUN1 Deficient Mice Reveals a Distinct Role of SUN2 in Mammalian Meiotic LINC Complex Formation and Function Arf4 Is Required for Mammalian Development but Dispensable for Ciliary Assembly CEP-1,the Caenorhabditis elegans p53 Homolog,Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24 Cascades of Genetic Instability Resulting from Compromised Break-Induced Replication Chk2 and P53 Regulate the Transmission of Healed Chromosomes in the Drosophila Male Germline Chromosome I Controls Chromosome II Replication in Vibrio cholerae Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation Classic Selective Sweeps Revealed by Massive Sequencing in Cattle Coherent Functional Modules Improve Transcription Factor Target Identification,Cooperativity Prediction,and Disease Association Comparative RNAi Screens in C. elegans and C. briggsae Reveal the Impact of Developmental System Drift on Gene Function Convergence of Light and ABA Signaling on the ABI5 Promoter Correction to: PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit (PLoS Genet,(2014),10,[2]) Correction to: Whole-Exome Sequencing Reveals a Rapid Change in the Frequency of Rare Functional Variants in a Founding Population of Humans (PLoS Genet,(2014) 10,[2]) DAAM Is Required for Thin Filament Formation and Sarcomerogenesis during Muscle Development in Drosophila DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans DNA Sequence Explains Seemingly Disordered Methylation Levels in Partially Methylated Domains of Mammalian Genomes Ddc2 Mediates Mec1 Activation through a Ddc1- or Dpb11-Independent Mechanism Distinct DNA Binding Sites Contribute to the TCF Transcriptional Switch in C. elegans and Drosophila Distinct Requirements for Cranial Ectoderm and Mesenchyme-Derived Wnts in Specification and Differentiation of Osteoblast and Dermal Progenitors Euchromatic Transposon Insertions Trigger Production of Novel Pi- and Endo-siRNAs at the Target Sites in the Drosophila Germline Extreme Population Differences in the Human Zinc Transporter ZIP4 (SLC39A4) Are Explained by Positive Selection in Sub-Saharan Africa Fifteen Years Later: Hard and Soft Selection Sweeps Confirm a Large Population Number for HIV In Vivo Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer Genome-Wide Association Study of Metabolic Traits Reveals Novel Gene-Metabolite-Disease Links Genomic Networks of Hybrid Sterility High-Resolution Profiling of Stationary-Phase Survival Reveals Yeast Longevity Factors and Their Genetic Interactions Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a Myc/p53-Dependent Bottleneck in Lymphomagenesis Insights into the Dekkera bruxellensis Genomic Landscape: Comparative Genomics Reveals Variations in Ploidy and Nutrient Utilisation Potential amongst Wine Isolates Integrated Genomic Characterization Reveals Novel,Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma Loss of Trabid,a New Negative Regulator of the Drosophila Immune-Deficiency Pathway at the Level of TAK1,Reduces Life Span Mammalian E-type Cyclins Control Chromosome Pairing,Telomere Stability and CDK2 Localization in Male Meiosis Mapping the Fitness Landscape of Gene Expression Uncovers the Cause of Antagonism and Sign Epistasis between Adaptive Mutations Mechanistically Distinct Mouse Models for CRX-Associated Retinopathy MicroRNA-133 Inhibits Behavioral Aggregation by Controlling Dopamine Synthesis in Locusts MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis Molecular Evidence for the Inverse Comorbidity between Central Nervous System Disorders and Cancers Detected by Transcriptomic Meta-analyses Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice Mutation of SLC35D3 Causes Metabolic Syndrome by Impairing Dopamine Signaling in Striatal D1 Neurons NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly Natural Polymorphisms in Tap2 Influence Negative Selection and CD4:CD8 Lineage Commitment in the Rat Negative Feedback and Transcriptional Overshooting in a Regulatory Network for Horizontal Gene Transfer Oxidative Stress Is Not a Major Contributor to Somatic Mitochondrial DNA Mutations Plasma Cholesterol-Induced Lesion Networks Activated before Regression of Early,Mature,and Advanced Atherosclerosis Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli Selective Disruption of Aurora C Kinase Reveals Distinct Functions from Aurora B Kinase during Meiosis in Mouse Oocytes Serine Carboxypeptidase SCPEP1 and Cathepsin A Play Complementary Roles in Regulation of Vasoconstriction via Inactivation of Endothelin-1 Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging Sex-Specific Embryonic Gene Expression in Species with Newly Evolved Sex Chromosomes Targeted Ablation of Nesprin 1 and Nesprin 2 from Murine Myocardium Results in Cardiomyopathy,Altered Nuclear Morphology and Inhibition of the Biomechanical Gene Response The Caenorhabditis elegans Iodotyrosine Deiodinase Ortholog SUP-18 Functions through a Conserved Channel SC-Box to Regulate the Muscle Two-Pore Domain Potassium Channel SUP-9 The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted to Fluctuating Environments The Same but Different: Worms Reveal the Pervasiveness of Developmental System Drift The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic Kinetoplastids Reveals a Parasite Tailored for Plants Transcriptome-Wide Analyses of 5′-Ends in RNase J Mutants of a Gram-Positive Pathogen Reveal a Role in RNA Maturation,Regulation and Degradation Transcriptomics and Functional Genomics of ROS-Induced Cell Death Regulation by RADICAL-INDUCED CELL DEATH1 Transmission Distortion Affecting Human Noncrossover but Not Crossover Recombination: A Hidden Source of Meiotic Drive Uncoupling of Molecular Maturation from Peripheral Target Innervation in Nociceptors Expressing a Chimeric TrkA/TrkC Receptor Within-Host Spatiotemporal Dynamics of Plant Virus Infection at the Cellular Level X Chromosome Control of Meiotic Chromosome Synapsis in Mouse Inter-Subspecific Hybrids Zfp322a Regulates Mouse ES Cell Pluripotency and Enhances Reprogramming Efficiency miR-100 Induces Epithelial-Mesenchymal Transition but Suppresses Tumorigenesis,Migration and Invasion