plos genetics سال:2014 - دوره:10

Fa | Ar | En


plos genetics
سال:2014 - دوره:10 - شماره:9

A Genetic Assay for Transcription Errors Reveals Multilayer Control of RNA Polymerase II Fidelity Admixture in Latin America: Geographic Structure,Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation An Evolutionarily Conserved Role for the Aryl Hydrocarbon Receptor in the Regulation of Movement Arabidopsis RRP6L1 and RRP6L2 Function in FLOWERING LOCUS C Silencing via Regulation of Antisense RNA Synthesis Atkinesin-13A Modulates Cell-Wall Synthesis and Cell Expansion in Arabidopsis thaliana via the THESEUS1 Pathway BMPs Regulate msx Gene Expression in the Dorsal Neuroectoderm of Drosophila and Vertebrates by Distinct Mechanisms Bipartite Recognition of DNA by TCF/Pangolin Is Remarkably Flexible and Contributes to Transcriptional Responsiveness and Tissue Specificity of Wingless Signaling Causal Variation in Yeast Sporulation Tends to Reside in a Pathway Bottleneck Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing Co-regulated Transcripts Associated to Cooperating eSNPs Define Bi-fan Motifs in Human Gene Networks Derlin-1 Regulates Mutant VCP-Linked Pathogenesis and Endoplasmic Reticulum Stress-Induced Apoptosis Differential Management of the Replication Terminus Regions of the Two Vibrio cholerae Chromosomes during Cell Division Differential Responses to Wnt and PCP Disruption Predict Expression and Developmental Function of Conserved and Novel Genes in a Cnidarian Dopamine Signaling Leads to Loss of Polycomb Repression and Aberrant Gene Activation in Experimental Parkinsonism Eliminating Both Canonical and Short-Patch Mismatch Repair in Drosophila melanogaster Suggests a New Meiotic Recombination Model Evidence for Widespread Positive and Negative Selection in Coding and Conserved Noncoding Regions of Capsella grandiflora GLD-4-Mediated Translational Activation Regulates the Size of the Proliferative Germ Cell Pool in the Adult C. elegans Germ Line Genome Wide Association Studies Using a New Nonparametric Model Reveal the Genetic Architecture of 17 Agronomic Traits in an Enlarged Maize Association Panel Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias HEATR2 Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus Hidden Diversity in Honey Bee Gut Symbionts Detected by Single-Cell Genomics Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation Hydroxymethylated Cytosines Are Associated with Elevated C to G Transversion Rates Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster Interspecific Tests of Allelism Reveal the Evolutionary Timing and Pattern of Accumulation of Reproductive Isolation Mutations Local Effect of Enhancer of Zeste-Like Reveals Cooperation of Epigenetic and cis-Acting Determinants for Zygotic Genome Rearrangements Low Levels of p53 Protein and Chromatin Silencing of p53 Target Genes Repress Apoptosis in Drosophila Endocycling Cells Memory and Fitness Optimization of Bacteria under Fluctuating Environments Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding,Histone Modifications,and Gene Expression Levels Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis Neurospora WC-1 Recruits SWI/SNF to Remodel frequency and Initiate a Circadian Cycle Nipbl and Mediator Cooperatively Regulate Gene Expression to Control Limb Development Obesity-Linked Homologues TfAP-2 and Twz Establish Meal Frequency in Drosophila melanogaster Out of Balance: R-loops in Human Disease PRO40 Is a Scaffold Protein of the Cell Wall Integrity Pathway,Linking the MAP Kinase Module to the Upstream Activator Protein Kinase C Positive Selection and Multiple Losses of the LINE-1-Derived L1TD1 Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency Regulation of Arabidopsis Flowering by the Histone Mark Readers MRG1/2 via Interaction with CONSTANS to Modulate FT Expression Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence Rejuvenation of Meiotic Cohesion in Oocytes during Prophase I Is Required for Chiasma Maintenance and Accurate Chromosome Segregation Requirement for Drosophila SNMP1 for Rapid Activation and Termination of Pheromone-Induced Activity Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria Role for Circadian Clock Genes in Seasonal Timing: Testing the Bünning Hypothesis SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene Stress-Induced Nuclear RNA Degradation Pathways Regulate Yeast Bromodomain Factor 2 to Promote Cell Survival Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure The Actomyosin Machinery Is Required for Drosophila Retinal Lumen Formation The Association of the Vanin-1 N131S Variant with Blood Pressure Is Mediated by Endoplasmic Reticulum-Associated Degradation and Loss of Function The Drosophila MAPK p38c Regulates Oxidative Stress and Lipid Homeostasis in the Intestine The Olfactory Transcriptomes of Mice The Proprotein Convertase KPC-1/Furin Controls Branching and Self-avoidance of Sensory Dendrites in Caenorhabditis elegans The Tandem Repeats Enabling Reversible Switching between the Two Phases of β-Lactamase Substrate Spectrum The Vip1 Inositol Polyphosphate Kinase Family Regulates Polarized Growth and Modulates the Microtubule Cytoskeleton in Fungi Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers Trans-kingdom Cross-Talk: Small RNAs on the Move Translational Regulation of the DOUBLETIME/CKIδ/ε Kinase by LARK Contributes to Circadian Period Modulation Translational Regulation of the Drosophila Post-Translational Circadian Mechanism Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control Widespread Genome Reorganization of an Obligate Virus Mutualist [No title available] tRNA Modifying Enzymes,NSUN2 and METTL1,Determine Sensitivity to 5-Fluorouracil in HeLa Cells