plos genetics سال:2012 - دوره:8

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plos genetics
سال:2012 - دوره:8 - شماره:10

A Likelihood-Based Framework for Variant Calling and De Novo Mutation Detection in Families A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse Calpain-5 Mutations Cause Autoimmune Uveitis,Retinal Neovascularization,and Photoreceptor Degeneration Cdon Mutation and Fetal Ethanol Exposure Synergize to Produce Midline Signaling Defects and Holoprosencephaly Spectrum Disorders in Mice Classical Genetics Meets Next-Generation Sequencing: Uncovering a Genome-Wide Recombination Map in Drosophila melanogaster Cofilin-1: A Modulator of Anxiety in Mice Comparative Genomics Suggests an Independent Origin of Cytoplasmic Incompatibility in Cardinium hertigii Comparison of Family History and SNPs for Predicting Risk of Complex Disease Cul3 and the BTB Adaptor Insomniac Are Key Regulators of Sleep Homeostasis and a Dopamine Arousal Pathway in Drosophila Cytokinesis-Based Constraints on Polarized Cell Growth in Fission Yeast Deep Genome-Wide Measurement of Meiotic Gene Conversion Using Tetrad Analysis in Arabidopsis thaliana Deposition of Histone Variant H2A.Z within Gene Bodies Regulates Responsive Genes Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation Embryos of Robertsonian Translocation Carriers Exhibit a Mitotic Interchromosomal Effect That Enhances Genetic Instability during Early Development Faster-X Evolution of Gene Expression in Drosophila Full-Length Synaptonemal Complex Grows Continuously during Meiotic Prophase in Budding Yeast Functional Antagonism between Sas3 and Gcn5 Acetyltransferases and ISWI Chromatin Remodelers Increasing Signal Specificity of the TOL Network of Pseudomonas putida mt-2 by Rewiring the Connectivity of the Master Regulator XylR It Was Heaven: An Interview with Evelyn Witkin Loss of Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant persephone MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells Maize Unstable factor for orange1 Is Required for Maintaining Silencing Associated with Paramutation at the pericarp color1 and booster1 Loci Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity Morphogenesis and Cell Fate Determination within the Adaxial Cell Equivalence Group of the Zebrafish Myotome Muscle-Specific Splicing Factors ASD-2 and SUP-12 Cooperatively Switch Alternative Pre-mRNA Processing Patterns of the ADF/Cofilin Gene in Caenorhabditis elegans Mutations in Hedgehog Acyltransferase (Hhat) Perturb Hedgehog Signaling,Resulting in Severe Acrania-Holoprosencephaly-Agnathia Craniofacial Defects New Partners in Regulation of Gene Expression: The Enhancer of Trithorax and Polycomb Corto Interacts with Methylated Ribosomal Protein L12 Via Its Chromodomain Phosphatase-Dead Myotubularin Ameliorates X-Linked Centronuclear Myopathy Phenotypes in Mice RAB-Like 2 Has an Essential Role in Male Fertility,Sperm Intra-Flagellar Transport,and Tail Assembly Recovery of Arrested Replication Forks by Homologous Recombination Is Error-Prone Regulation of ATG4B Stability by RNF5 Limits Basal Levels of Autophagy and Influences Susceptibility to Bacterial Infection Specific Missense Alleles of the Arabidopsis Jasmonic Acid Co-Receptor COI1 Regulate Innate Immune Receptor Accumulation and Function The Contribution of RNA Decay Quantitative Trait Loci to Inter-Individual Variation in Steady-State Gene Expression Levels The Date of Interbreeding between Neandertals and Modern Humans The Many Landscapes of Recombination in Drosophila melanogaster The Paramecium Germline Genome Provides a Niche for Intragenic Parasitic DNA: Evolutionary Dynamics of Internal Eliminated Sequences The SET-Domain Protein SUVR5 Mediates H3K9me2 Deposition and Silencing at Stimulus Response Genes in a DNA Methylation-Independent Manner Topoisomerase II- and Condensin-Dependent Breakage of MEC1ATR-Sensitive Fragile Sites Occurs Independently of Spindle Tension,Anaphase,or Cytokinesis Use of Pleiotropy to Model Genetic Interactions in a Population Variants Affecting Exon Skipping Contribute to Complex Traits Viral Evasion of a Bacterial Suicide System by RNA-Based Molecular Mimicry Enables Infectious Altruism