plos genetics سال:2012 - دوره:8

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plos genetics
سال:2012 - دوره:8 - شماره:12

A Framework for the Establishment of a Cnidarian Gene Regulatory Network for Endomesoderm Specification: The Inputs of ß-Catenin/TCF Signaling A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation A Histone Deacetylase Adjusts Transcription Kinetics at Coding Sequences during Candida albicans Morphogenesis A Mechanism of Gene Amplification Driven by Small DNA Fragments A Mystery Unraveled: Essentiality of RNase III in Bacillus subtilis Is Caused by Resident Prophages A New Isolation with Migration Model along Complete Genomes Infers Very Different Divergence Processes among Closely Related Great Ape Species A Polycomb Group Protein Is Retained at Specific Sites on Chromatin in Mitosis A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells A Yeast GSK-3 Kinase Mck1 Promotes Cdc6 Degradation to Inhibit DNA Re-Replication ATX1-Generated H3K4me3 Is Required for Efficient Elongation of Transcription,Not Initiation,at ATX1-Regulated Genes An Allele of an Ancestral Transcription Factor Dependent on a Horizontally Acquired Gene Product An Excess of Gene Expression Divergence on the X Chromosome in Drosophila Embryos: Implications for the Faster-X Hypothesis Approaching the Functional Annotation of Fungal Virulence Factors Using Cross-Species Genetic Interaction Profiling Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent Chromosome Fragile Sites in Arabidopsis Harbor Matrix Attachment Regions That May Be Associated with Ancestral Chromosome Rearrangement Events Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae Deciphering the Transcriptional-Regulatory Network of Flocculation in Schizosaccharomyces pombe Defining the Pathways Underlying the Prolonged PR Interval in Atrioventricular Conduction Disease Diapause Formation and Downregulation of Insulin-Like Signaling via DAF-16/FOXO Delays Axonal Degeneration and Neuronal Loss Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction Dnmt3a Protects Active Chromosome Domains against Cancer-Associated Hypomethylation Dynamic and Differential Regulation of Stem Cell Factor FoxD3 in the Neural Crest Is Encrypted in the Genome Evidence for the Robustness of Protein Complexes to Inter-Species Hybridization Excessive Astrocyte-Derived Neurotrophin-3 Contributes to the Abnormal Neuronal Dendritic Development in a Mouse Model of Fragile X Syndrome Genes Contributing to Pain Sensitivity in the Normal Population: An Exome Sequencing Study Genes That Act Downstream of Sensory Neurons to Influence Longevity,Dauer Formation,and Pathogen Responses in Caenorhabditis elegans Genetic Adaptation Associated with Genome-Doubling in Autotetraploid Arabidopsis arenosa Genome-Wide Association Study Implicates Testis-Sperm Specific FKBP6 as a Susceptibility Locus for Impaired Acrosome Reaction in Stallions Genome-Wide Fine-Scale Recombination Rate Variation in Drosophila melanogaster Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function Histone Deacetylase HDA6 Is Functionally Associated with AS1 in Repression of KNOX Genes in Arabidopsis Identification of Novel Type 2 Diabetes Candidate Genes Involved in the Crosstalk between the Mitochondrial and the Insulin Signaling Systems Identification of Orch3,a Locus Controlling Dominant Resistance to Autoimmune Orchitis,as Kinesin Family Member 1C Insertion/Deletion Polymorphisms in the ΔNp63 Promoter Are a Risk Factor for Bladder Exstrophy Epispadias Complex Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets Long-Range Regulatory Polymorphisms Affecting a GABA Receptor Constitute a Quantitative Trait Locus (QTL) for Social Behavior in Caenorhabditis elegans Mi2β Is Required for γ-Globin Gene Silencing: Temporal Assembly of a GATA-1-FOG-1-Mi2 Repressor Complex in β-YAC Transgenic Mice Natural Variation at the FRD3 MATE Transporter Locus Reveals Cross-Talk between Fe Homeostasis and Zn Tolerance in Arabidopsis thaliana On Lung Function and Interactions Using Genome-Wide Data PEP1 of Arabis alpina Is Encoded by Two Overlapping Genes That Contribute to Natural Genetic Variation in Perennial Flowering Polycomb Controls Gliogenesis by Regulating the Transient Expression of the Gcm/Glide Fate Determinant Population Genomics of Inversion Polymorphisms in Drosophila melanogaster Population Genomics of Sub-Saharan Drosophila melanogaster: African Diversity and Non-African Admixture Population Genomics of the Wolbachia Endosymbiont in Drosophila melanogaster Pre-Disposition and Epigenetics Govern Variation in Bacterial Survival upon Stress RecX Facilitates Homologous Recombination by Modulating RecA Activities Recessive Mutations in SPTBN2 Implicate β-III Spectrin in Both Cognitive and Motor Development Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing-Based Approach Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation SLI-1 Cbl Inhibits the Engulfment of Apoptotic Cells in C. elegans through a Ligase-Independent Function Spreading of Heterochromatin Is Limited to Specific Families of Maize Retrotransposons Systematic Identification of Rhythmic Genes Reveals camk1gb as a New Element in the Circadian Clockwork Systems Genetic Analysis of Osteoblast-Lineage Cells Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex Reversals The Chromosomal Proteins JIL-1 and Z4/Putzig Regulate the Telomeric Chromatin in Drosophila melanogaster The Effective Population Size of Malaria Mosquitoes: Large Impact of Vector Control The Essential Function of B. subtilis RNase III Is to Silence Foreign Toxin Genes The GATA Transcription Factor egl-27 Delays Aging by Promoting Stress Resistance in Caenorhabditis elegans The Genetic Architecture of Adaptations to High Altitude in Ethiopia Translation in Giant Viruses: A Unique Mixture of Bacterial and Eukaryotic Termination Schemes Wheat TILLING Mutants Show That the Vernalization Gene VRN1 Down-Regulates the Flowering Repressor VRN2 in Leaves but Is Not Essential for Flowering