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plos genetics
  
سال:2013 - دوره:9 - شماره:10
  
 
A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2
  
 
A Genetic RNAi Screen for IP3/Ca2+ Coupled GPCRs in Drosophila Identifies the PdfR as a Regulator of Insect Flight
  
 
A KH-Domain RNA-Binding Protein Interacts with FIERY2/CTD Phosphatase-Like 1 and Splicing Factors and Is Important for Pre-mRNA Splicing in Arabidopsis
  
 
A Minimal Nitrogen Fixation Gene Cluster from Paenibacillus sp. WLY78 Enables Expression of Active Nitrogenase in Escherichia coli
  
 
A Mutation in the SUV39H2 Gene in Labrador Retrievers with Hereditary Nasal Parakeratosis (HNPK) Provides Insights into the Epigenetics of Keratinocyte Differentiation
  
 
A Novel Actin mRNA Splice Variant Regulates ACTG1 Expression
  
 
A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression
  
 
A Novel Role for Ecdysone in Drosophila Conditioned Behavior: Linking GPCR-Mediated Non-canonical Steroid Action to cAMP Signaling in the Adult Brain
  
 
A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability
  
 
A Review of Bacteria-Animal Lateral Gene Transfer May Inform Our Understanding of Diseases like Cancer
  
 
ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation
  
 
Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization
  
 
Both Rare and De Novo Copy Number Variants Are Prevalent in Agenesis of the Corpus Callosum but Not in Cerebellar Hypoplasia or Polymicrogyria
  
 
Chimeric Protein Complexes in Hybrid Species Generate Novel Phenotypes
  
 
Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans
  
 
Condensin II Subunit dCAP-D3 Restricts Retrotransposon Mobilization in Drosophila Somatic Cells
  
 
Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition
  
 
Cooperation between RUNX1-ETO9a and Novel Transcriptional Partner KLF6 in Upregulation of Alox5 in Acute Myeloid Leukemia
  
 
Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling Pathway
  
 
Coordination of Cell Proliferation and Cell Fate Determination by CES-1 Snail
  
 
Correlated Occurrence and Bypass of Frame-Shifting Insertion-Deletions (InDels) to Give Functional Proteins
  
 
De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences
  
 
Defending Sperm Function
  
 
Different Roles of Eukaryotic MutS and MutL Complexes in Repair of Small Insertion and Deletion Loops in Yeast
  
 
Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation
  
 
Distinct Regulatory Mechanisms Act to Establish and Maintain Pax3 Expression in the Developing Neural Tube
  
 
Dominant Mutations in S. cerevisiae PMS1 Identify the Mlh1-Pms1 Endonuclease Active Site and an Exonuclease 1-Independent Mismatch Repair Pathway
  
 
Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection
  
 
Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer
  
 
Evolutionary Change within a Bipotential Switch Shaped the Sperm/Oocyte Decision in Hermaphroditic Nematodes
  
 
Evolutionary Tuning of Protein Expression Levels of a Positively Autoregulated Two-Component System
  
 
FliZ Is a Global Regulatory Protein Affecting the Expression of Flagellar and Virulence Genes in Individual Xenorhabdus nematophila Bacterial Cells
  
 
Function and Evolution of DNA Methylation in Nasonia vitripennis
  
 
Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse
  
 
Genetic Regulation of Caenorhabditis elegans Lysosome Related Organelle Function
  
 
Genome Wide Analysis Reveals Zic3 Interaction with Distal Regulatory Elements of Stage Specific Developmental Genes in Zebrafish
  
 
Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic
  
 
Genome-Wide Analysis of Cell Type-Specific Gene Transcription during Spore Formation in Clostridium difficile
  
 
Genome-Wide High-Resolution Mapping of UV-Induced Mitotic Recombination Events in Saccharomyces cerevisiae
  
 
Genome-Wide and Cell-Specific Epigenetic Analysis Challenges the Role of Polycomb in Drosophila Spermatogenesis
  
 
High Throughput Sequencing Reveals Alterations in the Recombination Signatures with Diminishing Spo11 Activity
  
 
How to Choose the Right Mate
  
 
Hsp70-Hsp40 Chaperone Complex Functions in Controlling Polarized Growth by Repressing Hsf1-Driven Heat Stress-Associated Transcription
  
 
Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila
  
 
Identification of 526 Conserved Metazoan Genetic Innovations Exposes a New Role for Cofactor E-like in Neuronal Microtubule Homeostasis
  
 
Incorporating Motif Analysis into Gene Co-expression Networks Reveals Novel Modular Expression Pattern and New Signaling Pathways
  
 
Inhibition of the Mitotic Exit Network in Response to Damaged Telomeres
  
 
Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes,and Cytokine Signaling Genes in Crohn's Disease
  
 
Limiting of the Innate Immune Response by SF3A-Dependent Control of MyD88 Alternative mRNA Splicing
  
 
Loss of miR-10a Activates Lpo and Collaborates with Activated Wnt Signaling in Inducing Intestinal Neoplasia in Female Mice
  
 
Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates
  
 
Mismatch Repair Genes Mlh1 and Mlh3 Modify CAG Instability in Huntington's Disease Mice: Genome-Wide and Candidate Approaches
  
 
Mobility of the Native Bacillus subtilis Conjugative Plasmid pLS20 Is Regulated by Intercellular Signaling
  
 
Multiple Signaling Pathways Coordinate to Induce a Threshold Response in a Chordate Embryo
  
 
Multiple bHLH Proteins form Heterodimers to Mediate CRY2-Dependent Regulation of Flowering-Time in Arabidopsis
  
 
Natural Genetic Variation of Integrin Alpha L (Itgal) Modulates Ischemic Brain Injury in Stroke
  
 
Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies
  
 
PNUTS/PP1 Regulates RNAPII-Mediated Gene Expression and Is Necessary for Developmental Growth
  
 
Partial Deletion of Chromosome 8 β-defensin Cluster Confers Sperm Dysfunction and Infertility in Male Mice
  
 
Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture
  
 
Playing the Field: Sox10 Recruits Different Partners to Drive Central and Peripheral Myelination
  
 
Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression
  
 
Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2
  
 
Reverse PCA,a Systematic Approach for Identifying Genes Important for the Physical Interaction between Protein Pairs
  
 
Robust Demographic Inference from Genomic and SNP Data
  
 
SUMO Localizes to the Central Element of Synaptonemal Complex and Is Required for the Full Synapsis of Meiotic Chromosomes in Budding Yeast
  
 
Specific Tandem Repeats Are Sufficient for Paramutation-Induced Trans-Generational Silencing
  
 
Stimulation of mTORC1 with L-leucine Rescues Defects Associated with Roberts Syndrome
  
 
Survival of the Replication Checkpoint Deficient Cells Requires MUS81-RAD52 Function
  
 
Systematic Unraveling of the Unsolved Pathway of Nicotine Degradation in Pseudomonas
  
 
The Bacterial Response Regulator ArcA Uses a Diverse Binding Site Architecture to Regulate Carbon Oxidation Globally
  
 
The Deacetylase Sir2 from the Yeast Clavispora lusitaniae Lacks the Evolutionarily Conserved Capacity to Generate Subtelomeric Heterochromatin
  
 
The Drosophila eve Insulator Homie Promotes eve Expression and Protects the Adjacent Gene from Repression by Polycomb Spreading
  
 
The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters
  
 
The Human Nuclear Poly(A)-Binding Protein Promotes RNA Hyperadenylation and Decay
  
 
The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells
  
 
The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis
  
 
The Serum Resistome of a Globally Disseminated Multidrug Resistant Uropathogenic Escherichia coli Clone
  
 
The Spore Differentiation Pathway in the Enteric Pathogen Clostridium difficile
  
 
The Transacting Factor CBF-A/Hnrnpab Binds to the A2RE/RTS Element of Protamine 2 mRNA and Contributes to Its Translational Regulation during Mouse Spermatogenesis
  
 
The Transcription Factors Sox10 and Myrf Define an Essential Regulatory Network Module in Differentiating Oligodendrocytes
  
 
Tracking Proliferative History in Lymphocyte Development with Cre-Mediated Sister Chromatid Recombination
  
 
Transcription Termination and Chimeric RNA Formation Controlled by Arabidopsis thaliana FPA
  
 
Two Portable Recombination Enhancers Direct Donor Choice in Fission Yeast Heterochromatin
  
 
Xbp1 Directs Global Repression of Budding Yeast Transcription during the Transition to Quiescence and Is Important for the Longevity and Reversibility of the Quiescent State
  
 
Yeast Tdh3 (Glyceraldehyde 3-Phosphate Dehydrogenase) Is a Sir2-Interacting Factor That Regulates Transcriptional Silencing and rDNA Recombination
  
 
tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans
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