plos genetics سال:2010 - دوره:6

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plos genetics
سال:2010 - دوره:6 - شماره:11

A buoyancy-based screen of drosophila larvae for fat- storage mutants reveals a role for Sir2 in coupling fat Storage to Nutrient Availability A coastal cline in sodium accumulation in Arabidopsis thaliana is driven by natural variation of the sodium transporter AtHKT1;1 A functional genomics approach identifies candidate effectors from the aphid species Myzus persicae (green peach aphid) A novel zf-MYND protein,CHB-3,mediates guanylyl cyclase localization to sensory cilia and controls body size of Caenorhabditis elegans ATM limits incorrect end utilization during non- homologous end joining of multiple chromosome breaks Altered DNA methylation in leukocytes with trisomy 21 An evolutionary framework for association testing in resequencing studies Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis Beyond QTL cloning CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-igf2 imprinting control region in prospermatogonia Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation Conflict between noise and plasticity in yeast DNA methylation and normal chromosome behavior in neurospora depend on five components of a histone methyltransferase complex,DCDC Endless forms most viral Endogenous viral elements in animal genomes Epigenetic silencing of spermatocyte-specific and neuronal genes by SUMO modification of the transcription factor sp3 Essential functions of the histone demethylase Lid Genetic basis of growth adaptation of Escherichia coli after deletion of pgi,a major metabolic gene Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential Pleiotropic effects on bone Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid a Genome-wide effects of long-term divergent selection Hormad1 mutation disrupts synaptonemal complex formation,recombination,and chromosome segregation in mammalian meiosis Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells Leptotene/Zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25 Mismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε Nomadic enhancers: Tissue-specific cis-regulatory elements of yellow have divergent genomic positions among Drosophila species Nucleolin is required for DNA methylation state and the expression of rRNA gene variants in Arabidopsis thaliana RACK-1 acts with Rac GTpase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch Sarcomere formation occurs by the assembly of multiple latent protein complexes Systematic dissection and trajectory-scanning mutagenesis of the molecular interface that ensures specificity of two-component signaling pathways The Caenorhabditis elegans kinesin-3 motor UNC-104/KIF1A is degraded upon loss of specific binding to cargo The cellular robustness by genetic redundancy in budding yeast The complex genetic architecture of the metabolome The functional interplay between protein kinase CK2 and cca1 transcriptional activity is essential for clock temperature compensation in Arabidopsis The parental non-equivalence of imprinting control regions during mammalian development and evolution The transcriptional regulator Rok binds A+T-rich DNA and is involved in repression of a mobile genetic element in Bacillus subtilis