plos genetics سال:2011 - دوره:7

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plos genetics
سال:2011 - دوره:7 - شماره:8

A broad brush,global overview of bacterial sexuality A comprehensive map of mobile element insertion polymorphisms in humans A pre-mrna-associating factor links endogenous sirnas to chromatin regulation An emt-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype Analysis of dna methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation B chromosomes have a functional effect on female sex determination in lake victoria cichlid fishes Celsr3 is required for normal development of gaba circuits in the inner retina Chromosome painting reveals asynaptic full alignment of homologs and him-8-dependent remodeling of x chromosome territories during caenorhabditis elegans meiosis Discovery of sexual dimorphisms in metabolic and genetic biomarkers Distinct cdk1 requirements during single-strand annealing,noncrossover,and crossover recombination Dlx and sp6-9 control optic cup regeneration in a prototypic eye Dna methylation and histone modifications regulate de novo shoot regeneration in arabidopsis by modulating wuschel expression and auxin signaling Evidence for hitchhiking of deleterious mutations within the human genome Frequent beneficial mutations during single-colony serial transfer of streptococcus pneumoniae Fus and tardbp but not sod1 interact in genetic models of amyotrophic lateral sclerosis Gamma-tubulin is required for bipolar spindle assembly and for proper kinetochore microtubule attachments during prometaphase i in drosophila oocytes Genetic architecture of a reinforced,postmating,reproductive isolation barrier between neurospora species indicates evolution via natural selection Genetic architecture of aluminum tolerance in rice (oryza sativa) determined through genome-wide association analysis and qtl mapping Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases Genome-wide association analysis of incident coronary heart disease (chd) in african americans: A short report Genome-wide gene-environment study identifies glutamate receptor gene grin2a as a parkinson's disease modifier gene via interaction with coffee Genomic analysis of the necrotrophic fungal pathogens sclerotinia sclerotiorum and botrytis cinerea Global chromosomal structural instability in a subpopulation of starving escherichia coli cells Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia Hunger artists: Yeast adapted to carbon limitation show trade-offs under carbon sufficiency Identification of functional toxin/immunity genes linked to contact-dependent growth inhibition (cdi) and rearrangement hotspot (rhs) systems Increased rpa1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndrome Ku must load directly onto the chromosome end in order to mediate its telomeric functions Mk2-dependent p38b signalling protects drosophila hindgut enterocytes against jnk-induced apoptosis under chronic stress Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation Natural polymorphism in bul2 links cellular amino acid availability with chronological aging and telomere maintenance in yeast Ongoing phenotypic and genomic changes in experimental coevolution of rna bacteriophage qβ and escherichia coli Pervasive sharing of genetic effects in autoimmune disease Polo,greatwall,and protein phosphatase pp2a jostle for pole position Pp2a-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos Predisposition to cancer caused by genetic and functional defects of mammalian atad5 Regulation of caenorhabditis elegans p53/cep-1-dependent germ cell apoptosis by ras/mapk signaling Specification of drosophila corpora cardiaca neuroendocrine cells from mesoderm is regulated by notch signaling Suppression of scant identifies endos as a substrate of greatwall kinase and a negative regulator of protein phosphatase 2a in mitosis Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection The caenorhabditis elegans gata factor elt-1 works through the cell proliferation regulator bro-1 and the fusogen eff-1 to maintain the seam stem-like fate The caenorhabditis elegans t-box factor mls-1 requires groucho co-repressor interaction for uterine muscle specification The repertoire of ice in prokaryotes underscores the unity,diversity,and ubiquity of conjugation Trans-eqtls reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes,with a major role for the hla Variance of gene expression identifies altered network constraints in neurological disease