Deltamethrin toxicological profile of peridomestic Triatoma sordida in the North of Minas Gerais,Brazil

Background: in general,there was a large reduction in the occurrence of cases of chagas disease in the last decades in brazil. however,despite all of these efforts,there have been various reports of persistent reinfestations of t. sordida in a large part of the state of minas gerais,for reasons still little investigated. thus,this purpose of this study was to characterize the deltamethrin susceptibility profile of peridomestic t. sordida populations from north of minas gerais - brazil. methods: susceptibility to deltamethrin was assessed in seventeen peridomestic populations of t. sordida from north region of minas gerais,brazil. serial dilutions of deltamethrin in acetone (0.2 μl) were topically applied in first instar nymphs (f1,five days old,fasting,weight 1.2 ± 0.2 mg). dose response results were analyzed with polo program,determining the lethal doses,slope and resistance ratios (rr). results: susceptibility profile characterization of t. sordida populations revealed resistance ratios (rr50) ranging from 2.50 to 7.08. conclusions: in fact,we know very little about the real impact of the resistance ratios obtained in the laboratory bioassays on the effectiveness of the vector control activities in the field. thus,we prefer to refer to the populations with rr > 5 as populations with altered susceptibility. for these populations,the realization of laboratory and field trials,simultaneous and complementary,permitting the evaluation of both,is recommended. © 2015 pessoa et al.; licensee biomed central.