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Influence of inflammation on parasitism and area of experimental amoebic liver abscess: An immunohistochemical and morphometric study
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نویسنده
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costa c.a.x. ,fonseca t.h.s. ,oliveira f.m.s. ,santos j.f.g. ,gomes m.a. ,caliari m.v.
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منبع
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parasites and vectors - 2011 - دوره : 4 - شماره : 1
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چکیده
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The influence of inflammation on the number of trophozoites and on the murine amoebic liver abscess area following infection with entamoeba histolytica and e. dispar was evaluated. immunohistochemistry and digital morphometry were used to identify and quantify the trophozoites,neutrophils,macrophages,and lesions. positive correlation was observed between the number of trophozoites and inflammatory cells. a significant decrease in parasitism and inflammation in groups treated with dexamethasone was observed. the scarceness or absence of trophozoites in the treated groups suggest the importance of the inflammatory response in the production of amoebic hepatic abscesses in spite of the inherent virulence of the parasite being decisive in the establishment of the lesion. © 2011 costa et al; licensee biomed central ltd.
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آدرس
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programa de pás-graduaço em patologia,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais,brazil,departamento de patologia geral,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais, Brazil, departamento de parasitologia,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais, Brazil, programa de pás-graduaço em patologia,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais,brazil,departamento de patologia geral,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais, Brazil, hospital governador israel pinheiro - ipsemg,belo horizonte,minas gerais, Brazil, departamento de parasitologia,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais, Brazil, departamento de patologia geral,instituto de cincias biolágicas,universidade federal de minas gerais,av. antnio carlos 6627,belo horizonte,minas gerais, Brazil
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Authors
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