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Gene discovery in Triatoma infestans
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نویسنده
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avila m.l. ,tekiel v. ,moretti g. ,nicosia s. ,bua j. ,lammel e.m. ,stroppa m.m. ,de burgos n.m.g. ,sánchez d.o.
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منبع
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parasites and vectors - 2011 - دوره : 4 - شماره : 1
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چکیده
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Background. triatoma infestans is the most relevant vector of chagas disease in the southern cone of south america. since its genome has not yet been studied,sequencing of expressed sequence tags (ests) is one of the most powerful tools for efficiently identifying large numbers of expressed genes in this insect vector. results. in this work,we generated 826 ests,resulting in an increase of 47% in the number of ests available for t. infestans. these ests were assembled in 471 unique sequences,151 of which represent 136 new genes for the reduviidae family. conclusions. among the putative new genes for the reduviidae family,we identified and described an interesting subset of genes involved in development and reproduction,which constitute potential targets for insecticide development. © 2011 avila et al; licensee biomed central ltd.
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آدرس
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instituto de investigaciones biotecnolágicas,universidad nacional de san martín - conicet,edificio 24,av. gral paz 5445,b1650kna,san martín,provincia de buenos aires, Argentina, instituto de investigaciones biotecnolágicas,universidad nacional de san martín - conicet,edificio 24,av. gral paz 5445,b1650kna,san martín,provincia de buenos aires, Argentina, instituto de investigaciones biotecnolágicas,universidad nacional de san martín - conicet,edificio 24,av. gral paz 5445,b1650kna,san martín,provincia de buenos aires, Argentina, instituto de investigaciones biotecnolágicas,universidad nacional de san martín - conicet,edificio 24,av. gral paz 5445,b1650kna,san martín,provincia de buenos aires, Argentina, inst. nac. de parasitología,dr. m. fatala chaben,anlis c.g. malbrán,paseo colán 568,buenos aires, Argentina, dpto de microb.,parasitol. e inmunol.,fac. de medicina,universidad de buenos aires,buenos aires, Argentina, cat. de bioq. y biol. mol.,fac. de cs. médicas,universidad nacional de cárdoba, Argentina, cat. de bioq. y biol. mol.,fac. de cs. médicas,universidad nacional de cárdoba, Argentina, instituto de investigaciones biotecnolágicas,universidad nacional de san martín - conicet,edificio 24,av. gral paz 5445,b1650kna,san martín,provincia de buenos aires, Argentina
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Authors
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