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Sensitivity of a point of care tick-test for the development of Lyme borreliosis
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نویسنده
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sprong h. ,docters van leeuwen a. ,fonville m. ,harms m. ,van vliet a.j. ,van pelt w. ,ferreira j.a. ,van den wijngaard c.c.
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منبع
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parasites and vectors - 2013 - دوره : 6 - شماره : 1
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چکیده
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Background: a commercially available self-test for the detection of borrelia burgdorferi sensu lato in ticks was evaluated for its ability to predict erythema migrans formation. findings. the self-test was performed on 127 ixodes ricinus from 122 humans that reported tick bites at enrolment and occurrence of symptoms during follow-up. the self-test gave negative results on all the 122 individuals,14 of whom reported erythema migrans (em) at follow-up of which 10 were confirmed by their gp. the estimated sensitivity of the self-test for prediction of em formation is 0% (95% ci: 0%-28%). conclusions: this self-test is not suitable for reducing the number needed to treat in a post-exposure prophylaxis setting as it already missed all the obvious early lyme borreliosis cases. © 2013 sprong et al.; licensee biomed central ltd.
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کلیدواژه
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Ixodes ricinus; Lyme borreliosis; Post-exposure prophylaxis; Self-test; Validation
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آدرس
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centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, environmental systems analysis group,wageningen university,wageningen, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands, centre for infectious disease control netherlands,national institute for public health and environment,antonie van leeuwenhoeklaan 9,3720 ba,bilthoven, Netherlands
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Authors
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