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Bryothamnion seaforthii lectin relaxes vascular smooth muscle: Involvement of endothelium and NO synthase
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نویسنده
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lima r.f. ,criddle d.n. ,soares p.m.g. ,ribeiro s.p. ,cavada b.s. ,nascimento k.s. ,sampaio a.h. ,assreuy a.m.s.
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منبع
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protein and peptide letters - 2010 - دوره : 17 - شماره : 3 - صفحه:305 -310
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چکیده
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Bryothamnion seaforthii lectin (bsl) induced reversible concentration-related relaxation of endothelized aorta,maximal at 30μg/ml (ic50=4.8 ± 0.6μg/ml). this effect was inhibited by l-name and reversed by mucin,probably via interaction with a specific lectin-binding site on the endothelium activating nitric oxide synthase. © 2010 bentham science publishers ltd.
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کلیدواژه
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Agglutinin; Bryothamnion seaforthii; Lectin; Nitric oxide synthase; Red marine alga
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آدرس
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instituto superior de ciências biomédicas,ccs,universidade estadual do ceará,av. paranjana 1700,60740-000, Brazil, mrc secretory control research group,the physiological laboratory,university of liverpool,crown street, United Kingdom, departamento de morfologia,universidade federal do ceará,rua delmiro de farias s/n rodolfo teófilo, Brazil, instituto superior de ciências biomédicas,ccs,universidade estadual do ceará,av. paranjana 1700,60740-000, Brazil, departamento de engenharia de pesca and departa-mento de bioquimica e biologia molecular biomol-lab,universidade federal do ceará,av. mister hull s/n bloco 907, Brazil, departamento de engenharia de pesca and departa-mento de bioquimica e biologia molecular biomol-lab,universidade federal do ceará,av. mister hull s/n bloco 907, Brazil, departamento de engenharia de pesca and departa-mento de bioquimica e biologia molecular biomol-lab,universidade federal do ceará,av. mister hull s/n bloco 907, Brazil, instituto superior de ciências biomédicas,ccs,universidade estadual do ceará,av. paranjana 1700,60740-000, Brazil
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Authors
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