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A novel approach to predict protein-protein interactions related to Azheimer's disease based on complex network
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نویسنده
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yang j. ,jiang x.-f.
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منبع
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protein and peptide letters - 2010 - دوره : 17 - شماره : 3 - صفحه:356 -366
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چکیده
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A protein domain interaction prediction program was complied using c++ to predict whether a query protein could interact with other hub proteins. it is indicated that the proteins interacting with aatf (apoptosis-antagonizing transcription factor) possess a common conservative pattern: i-x(0,1)-e-x(2)-[a/e/n/t]-x-[e/k]. our method is attempted to integrate the characteristics of protein interaction network with the simplest building blocks-conservative patterns. © 2010 bentham science publishers ltd.
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کلیدواژه
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AD associated protein interaction network; Conservative interaction pattern; Signal pathway
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آدرس
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state key laboratory of pharmaceutical biotechnology,nanjing university, China, state key laboratory of pharmaceutical biotechnology,nanjing university, China
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Authors
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