Human Hsp70/Hsp90 organizing protein (Hop) D456G is a mixture of monomeric and dimeric species
|
|
|
|
|
|
|
|
نویسنده
|
|
|
منبع
|
protein and peptide letters - 2010 - دوره : 17 - شماره : 4 - صفحه:42 -498
|
|
چکیده
|
Hop is a tetratricopeptide repeat domain (tpr)-containing co-chaperone that is able to directly associate with both hsp70 and hsp90. previous data showed that the tpr2a-domain is the primary site for dimerization and that the tpr2b-domain may also play a role in dimerization. we present hop-d456g,a mutant within the tpr2b-domain,that is a mixture of monomeric and dimeric species. © 2010 bentham science publishers ltd.
|
|
کلیدواژه
|
Heat shock protein; Hop; Hsp90; Protein folding; Protein-protein interaction; TPR domain
|
|
آدرس
|
|
|
|
|
|
|
|
|
|
|