|
|
|
|
Furin cleavage of bacterial expressed Glutathione-S-Transferase-Pro- Transforming growth factor β1 fusion protein in vitro
|
|
|
|
|
|
|
|
نویسنده
|
kahle n.a. ,joffroy c. ,popp s.l. ,knabbe c. ,stope m.b.
|
|
منبع
|
protein and peptide letters - 2010 - دوره : 17 - شماره : 4 - صفحه:416 -418
|
|
چکیده
|
To investigate the processing of transforming growth factor β1 (tgfβ1) pro-protein by furin protease we expressed a gst-pro-tgfβ1 fusion protein in bacteria. analysis of the furin digestion pattern revealed the liberation of 12.5 kda tgfβ1 monomers. there was no evidence for cleavage of an alternative furin site within the pro-protein.
|
|
کلیدواژه
|
Furin; Proteolytic processing; Transforming growth factor β1
|
|
آدرس
|
dr. margarete fischer-bosch institute of clinical pharmacology, Germany, dr. margarete fischer-bosch institute of clinical pharmacology, Germany, dr. margarete fischer-bosch institute of clinical pharmacology, Germany, department of clinical chemistry,robert bosch hospital, Germany, dr. margarete fischer-bosch institute of clinical pharmacology, Germany
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|