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The two pathways for effective orthogonal protection of L-ornithine,for amino acylation of 5'-O-Pivaloyl nucleosides,describe the general and important role for the successful imitation,during the synthesis of the model substrates for the ribosomal mimic reaction
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نویسنده
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bayryamov s.g. ,vassilev n.g. ,petkov d.d.
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منبع
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protein and peptide letters - 2010 - دوره : 17 - شماره : 7 - صفحه:889 -898
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چکیده
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Bz(no2)-orn(boc)-och2cn was synthesized as an amino acid component with effective and successful orthogonal protection for amino acylation of 5'-o-pivaloyl nucleosides and preparation of substrates for model ribosome reactions. the synthesis was carried out using suitable combinations of the methods of peptide synthesis and modification of amino acids. © 2010 bentham science publishers ltd.
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کلیدواژه
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Conventional peptide synthesis; Ornithine; Orthogonal protection
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آدرس
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laboratory of biocatalysis,institute of organic chemistry,bulgarian academy of sciences,acad. bonchev str.,bld. 9, Bulgaria, laboratory of nuclear magnetic resonance,institute of organic chemistry,bulgarian academy of sciences, Bulgaria, laboratory of biocatalysis,institute of organic chemistry,bulgarian academy of sciences,acad. bonchev str.,bld. 9, Bulgaria
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Authors
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