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Adsorption and bioactivity of tyrosine hydroxylase on gold surfaces and nanoparticles
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نویسنده
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halskau ø. ,volden s. ,calvo a.c. ,martinez a. ,glomm w.r.
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منبع
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protein and peptide letters - 2010 - دوره : 17 - شماره : 11 - صفحه:1376 -1382
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چکیده
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Tyrosine hydroxylase is studied in terms of adsorption behaviour on gold surfaces and various passivating layers. results reveal differences in layer formation,where mercaptoundecanoic acid-coated gold shows the best potential in terms of adsorbed mass. nanoparticles with this coating are subsequently tested for enzymatic activity,which remains at attenuated levels. © 2010 bentham science publishers ltd.
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کلیدواژه
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Adsorption; Enzymatic activity; Gold nanoparticles; Parkinson's disease; Recombinant human tyrosine hydroxylase isoform 1 (hTH1); Stability
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آدرس
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department of biomedicine,university of bergen,jonas lies vei 91, Norway, department of chemical engineering,norwegian university of science and technology,sem scelands vei 4, Norway, department of biomedicine,university of bergen,jonas lies vei 91, Norway, department of biomedicine,university of bergen,jonas lies vei 91, Norway, department of chemical engineering,norwegian university of science and technology,sem scelands vei 4, Norway
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Authors
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