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Carbonyldiimidazole (CDI) mediated synthesis of N α- protected amino acid azides: Application to the one-pot preparation of ureidopeptides
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نویسنده
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vasantha b. ,vishwanatha t.m. ,sureshbabu v.v.
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منبع
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protein and peptide letters - 2011 - دوره : 18 - شماره : 11 - صفحه:1093 -1098
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چکیده
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Synthesis of n α-protected amino acyl azides starting from corresponding acids via the carbonyldiimidazole (cdi) activation is described. the protocol is extended for a one-pot preparation of ureido peptides that circumvents the isolation of acyl azide and isocyanate intermediates. the reaction was accomplished without using any additives and base. the protocol is simple,clean,high yielding and free from racemization. © 2011 bentham science publishers.
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کلیدواژه
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Acyl azide; CDI; One-pot reaction; Ureidopeptides
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آدرس
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department of studies in chemistry,central college campus,bangalore university,dr. b. r. ambedkar veedhi, India, department of studies in chemistry,central college campus,bangalore university,dr. b. r. ambedkar veedhi, India, department of studies in chemistry,central college campus,bangalore university,dr. b. r. ambedkar veedhi, India
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Authors
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