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Enzyme promiscuity in the hormone-sensitive lipase family of proteins
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نویسنده
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giuseppe m. ,luigia m. ,elena p. ,yan f. ,luigi m.
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منبع
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protein and peptide letters - 2012 - دوره : 19 - شماره : 2 - صفحه:144 -154
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چکیده
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The number of enzymes endowed with the capacity to catalyse other reactions than the main,physiological one,a feature that has been called promiscuity,is increasing at a fast pace. promiscuity is a highly pervasive phenomenon that is present at each level of life complexity. for enzymes,promiscuity encompasses interesting aspects related to their physiological role,evolution and biotechnological applications. herein,at first we will describe some general aspects of enzyme promiscuity and then we will report some examples from theα/βhydrolase superfamily of proteins,with particular emphasis to the hormone-sensitive lipase family. © 2012 bentham science publishers.
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کلیدواژه
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α/βhydrolase fold; Hormone-sensitive lipase family; Promiscuity
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آدرس
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istituto di biochimica delle proteine,consiglio nazionale delle ricerche,via. p. castellino 111,80131, Italy, istituto di biochimica delle proteine,consiglio nazionale delle ricerche,via. p. castellino 111,80131, Italy, istituto di biochimica delle proteine,consiglio nazionale delle ricerche,via. p. castellino 111,80131, Italy, key laboratory of moe for microbial metabolism,school of life science and biotechnology,shanghai jiao tong university, China, istituto di biochimica delle proteine,consiglio nazionale delle ricerche,via. p. castellino 111,80131, Italy
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Authors
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