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Integrating qualitative and quantitative tools for the detection and identification of lectins in major human diseases
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نویسنده
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ashraf g.m. ,perveen a. ,zaidi s.k. ,tabrez s. ,shakil s. ,ahmad a. ,haque r. ,ahsan j. ,kamal m.a. ,banu n.
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منبع
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protein and peptide letters - 2015 - دوره : 22 - شماره : 11 - صفحه:954 -962
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چکیده
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Lectins are the (glyco)proteins that recognize and bind to specific sugar moieties without altering their structure. galectins are mammalian lectins characterized by the presence of conserved 134 amino acids carbohydrate recognition domain and specificity for.-galactosides. the involvement of lectins in diverse biological spectrum,especially some deadly human diseases like cancer,neurological disorders and cardiovascular disorders has proclaimed them as one of the important components of glycobiology,thereby seeking the methods of their detection and identification heavily desirable. in the present manuscript,we have provided a comprehensive outline of various methods of detection and identification of lectins employed till date,with their needs and usage varying according to the level of infrastructure of laboratories and around the world. in addition,a vision for some quick,highly sensitive and advanced methods for lectin detection and identification for diagnostic and therapeutic of various diseases is also provided. © 2015 bentham science publishers.
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کلیدواژه
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Detection; Diseases; Galectin; Identification; Lectin; Therapy
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آدرس
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king fahd medical research center,king abdulaziz university,p. o. box 80216, Saudi Arabia, department of biochemistry,faculty of life sciences,aligarh muslim university, India, center of excellence in genomic medicine research,king abdulaziz university, Saudi Arabia, king fahd medical research center,king abdulaziz university,p. o. box 80216, Saudi Arabia, kacst technology innovation center for personalized medicine,king abdulaziz university,jeddah,saudi arabia,department of medical laboratory technology,faculty of applied medical sciences,king abdulaziz university, Saudi Arabia, amity institute of biotechnology,amity university uttar pradesh,lucknow, India, centre for biological sciences central university of bihar,patna, India, centre for biological sciences central university of bihar,patna, India, king fahd medical research center,king abdulaziz university,p. o. box 80216,jeddah,saudi arabia,enzymoic,hebersham, Australia, department of biochemistry,faculty of life sciences,aligarh muslim university,aligarh,india,college of medical rehabilitation,qassim university, Saudi Arabia
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Authors
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