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   Applying the ARRIVE Guidelines to an in Vivo Database  
   
نویسنده karp n.a. ,meehan t.f. ,morgan h. ,mason j.c. ,blake a. ,kurbatova n. ,smedley d. ,jacobsen j. ,mott r.f. ,iyer v. ,matthews p. ,melvin d.g. ,wells s. ,flenniken a.m. ,masuya h. ,wakana s. ,white j.k. ,lloyd k.c.k. ,reynolds c.l. ,paylor r. ,west d.b. ,svenson k.l. ,chesler e.j. ,de angelis m.h. ,tocchini-valentini g.p. ,sorg t. ,herault y. ,parkinson h. ,mallon a.-m. ,brown s.d.m.
منبع plos biology - 2015 - دوره : 13 - شماره : 5
چکیده    The animal research: reporting of in vivo experiments (arrive) guidelines were developed to address the lack of reproducibility in biomedical animal studies and improve the communication of research findings. while intended to guide the preparation of peer-reviewed manuscripts,the principles of transparent reporting are also fundamental for in vivo databases. here,we describe the benefits and challenges of applying the guidelines for the international mouse phenotyping consortium (impc),whose goal is to produce and phenotype 20,000 knockout mouse strains in a reproducible manner across ten research centres. in addition to ensuring the transparency and reproducibility of the impc,the solutions to the challenges of applying the arrive guidelines in the context of impc will provide a resource to help guide similar initiatives in the future. © 2015 karp et al.
آدرس mouse informatics group,wellcome trust sanger institute,cambridge, United Kingdom, samples,phenotypes and ontologies,european molecular biology laboratory—european bioinformatics institute,cambridge, United Kingdom, mammalian genetics unit,medical research council,harwell, United Kingdom, samples,phenotypes and ontologies,european molecular biology laboratory—european bioinformatics institute,cambridge, United Kingdom, mammalian genetics unit,medical research council,harwell, United Kingdom, samples,phenotypes and ontologies,european molecular biology laboratory—european bioinformatics institute,cambridge, United Kingdom, mouse informatics group,wellcome trust sanger institute,cambridge, United Kingdom, mouse informatics group,wellcome trust sanger institute,cambridge, United Kingdom, the wellcome trust centre for human genetics,oxford university,oxford, United Kingdom, cellular genetics,wellcome trust sanger institute,cambridge, United Kingdom, cellular genetics,wellcome trust sanger institute,cambridge, United Kingdom, mouse informatics group,wellcome trust sanger institute,cambridge, United Kingdom, mammalian genetics unit,medical research council,harwell, United Kingdom, toronto centre for phenogenomics,mount sinai hospital,toronto, Canada, bioresource center,riken,tsukuba, Japan, bioresource center,riken,tsukuba, Japan, mouse genetics project,wellcome trust sanger institute,cambridge, United Kingdom, mouse biology program,university of california davis,davis,ca, United States, molecular physiology and biophysics,baylor college of medicine,houston,tx, United States, molecular and human genetics,baylor college of medicine,houston,tx, United States, genetics,children's hospital oakland research institute,oakland,ca, United States, genetics,the jackson laboratory,bar habourme, United States, genetics,the jackson laboratory,bar habourme, United States, german mouse clinic-institute of experimental genetics,helmholtz zentrum münchen,neuherberg,germany,experimental genetics—center of life and food,technische universität münchen,freising-weihenstephan, Germany, monterotondo mouse clinic,cnr institute of cell biology and neurobiology,monterotondo,scalo, Italy, phenomin,centre national de la recherche scientifique,illkirch,france,institut clinique de la souris,université de strasbourg,illkirch,france,institut de génétique et de biologie moléculaire et cellulaire,institut national de la santé et de la recherche médicale u964,illkirch, France, phenomin,centre national de la recherche scientifique,illkirch,france,institut clinique de la souris,université de strasbourg,illkirch,france,institut de génétique et de biologie moléculaire et cellulaire,institut national de la santé et de la recherche médicale u964,illkirch, France, samples,phenotypes and ontologies,european molecular biology laboratory—european bioinformatics institute,cambridge, United Kingdom, mammalian genetics unit,medical research council,harwell, United Kingdom, mammalian genetics unit,medical research council,harwell, United Kingdom
 
     
   
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