plos biology سال:2012 - دوره:10

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plos biology
سال:2012 - دوره:10 - شماره:1

A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution Antarctic marine biodiversity and deep-sea hydrothermal vents Built-in timer delays differentiation Desperately seeking stable 50-year-old landscapes with patches and long,wide corridors Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal Functional clustering drives encoding improvement in a developing brain network during awake visual learning Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila New signaling chemicals spur worms to seek company Opening up the politics of knowledge and power in bioscience Pulsed feedback defers cellular differentiation Putting the pieces together: Integrative modeling platform software for structure determination of macromolecular assemblies Rapid evolution of enormous,multichromosomal genomes in flowering plant mitochondria with exceptionally high mutation rates Reconstructing speech from human auditory cortex Restoration of ailing wetlands Rise and fall,and rise again: Phagosome maturation is controlled by two kinases and one phosphatase Role of pleiotropy in the evolution of a cryptic developmental variation in Caenorhabditis elegans Sequential analysis of trans-SNARE formation in intracellular membrane fusion Stochastic expression of the interferon-β gene Structural and functional loss in restored wetland ecosystems Substrate specificity within a family of outer membrane carboxylate channels The chromosomal passenger complex activates Polo kinase at centromeres The discovery of new deep-sea hydrothermal vent communities in the Southern ocean and implications for biogeography Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization