|
|
|
|
Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
|
|
|
|
|
|
|
|
نویسنده
|
kalra h. ,simpson r.j. ,ji h. ,aikawa e. ,altevogt p. ,askenase p. ,bond v.c. ,borràs f.e. ,breakefield x. ,budnik v. ,buzas e. ,camussi g. ,clayton a. ,cocucci e. ,falcon-perez j.m. ,gabrielsson s. ,gho y.s. ,gupta d. ,harsha h.c. ,hendrix a. ,hill a.f. ,inal j.m. ,jenster g. ,krämer-albers e.-m. ,lim s.k. ,llorente a. ,lötvall j. ,marcilla a. ,mincheva-nilsson l. ,nazarenko i. ,nieuwland r. ,nolte-'t hoen e.n.m. ,pandey a. ,patel t. ,piper m.g. ,pluchino s. ,prasad t.s.k. ,rajendran l. ,raposo g. ,record m. ,reid g.e. ,sánchez-madrid f. ,schiffelers r.m. ,siljander p. ,stensballe a. ,stoorvogel w. ,taylor d. ,thery c. ,valadi h. ,van balkom b.w.m. ,vázquez j. ,vidal m. ,wauben m.h.m. ,yáñez-mó m. ,zoeller m. ,mathivanan s.
|
|
منبع
|
plos biology - 2012 - دوره : 10 - شماره : 12
|
|
چکیده
|
Extracellular vesicles (evs) are membraneous vesicles released by a variety of cells into their microenvironment. recent studies have elucidated the role of evs in intercellular communication,pathogenesis,drug,vaccine and gene-vector delivery,and as possible reservoirs of biomarkers. these findings have generated immense interest,along with an exponential increase in molecular data pertaining to evs. here,we describe vesiclepedia,a manually curated compendium of molecular data (lipid,rna,and protein) identified in different classes of evs from more than 300 independent studies published over the past several years. even though databases are indispensable resources for the scientific community,recent studies have shown that more than 50% of the databases are not regularly updated. in addition,more than 20% of the database links are inactive. to prevent such database and link decay,we have initiated a continuous community annotation project with the active involvement of ev researchers. the ev research community can set a gold standard in data sharing with vesiclepedia,which could evolve as a primary resource for the field. © 2012 kalra et al.
|
|
|
|
|
آدرس
|
department of biochemistry,la trobe institute for molecular science,la trobe university,melbourne,vic, Australia, department of biochemistry,la trobe institute for molecular science,la trobe university,melbourne,vic, Australia, department of biochemistry,la trobe institute for molecular science,la trobe university,melbourne,vic, Australia, cardiovascular medicine,brigham and women's hospital,harvard medical school,boston,ma, United States, tumor immunology programme,german cancer research center,heidelberg, Germany, department of medicine,yale medical school,new haven,ct, United States, department of microbiology,biochemistry,and immunology,morehouse school of medicine,atlanta,ga, United States, ivecat,lirad-bst,institut d'investigació germans trias i pujol,dept de biologia cellular,fisiologia i immunologia,universitat autònoma de barcelona,badalona, Spain, department of neurology,massachusetts general hospital,and neuroscience program,harvard medical school,boston,ma, United States, department of neurobiology,university of massachusetts medical school,worcester,ma, United States, department of genetics,cell- and immunobiology,semmelweis university,budapest, Hungary, department of internal medicine,centre for molecular biotechnology and centre for research in experimental medicine,torino, Italy, institute of cancer and genetics,school of medicine,cardiff university,velindre cancer centre,whitchurch,cardiff, United Kingdom, department of cell biology,harvard medical school,boston,ma,united states,immune disease institute and program in cellular and molecular medicine,boston children's hospital,boston,ma, United States, metabolomics unit,cic biogune,ciberehd,technology park of bizkaia,derio,bizkaia,spain,ikerbasque,basque foundation for science,bilbao, Spain, translational immunology unit,department of medicine solna,karolinska institutet,stockholm, Sweden, department of life science,pohang university of science and technology,pohang, South Korea, center of bioinformatics,institute of interdisciplinary studies,university of allahabad,allahabad, India, institute of bioinformatics,bangalore, India, laboratory of experimental cancer research,department of radiation oncology and experimental cancer research,ghent university hospital,ghent, Belgium, department of biochemistry and molecular biology,bio21 molecular science and biotechnology institute,the university of melbourne,parkville, Australia, cellular and molecular immunology research centre,faculty of life sciences,london metropolitan university,london, United Kingdom, department of urology,erasmus medical centre,rotterdam, Netherlands, department of molecular cell biology,johannes gutenberg university mainz,mainz, Germany, astar institute of medical biology and department of surgery,yong loo lin school of medicine,national university of singapore, Singapore, department of biochemistry,institute for cancer research,oslo university hospital-the norwegian radium hospital,oslo, Norway, krefting research centre,department of internal medicine and clinical nutrition,institute of medicine,sahlgrenska academy,university of gothenburg,gothenburg, Sweden, área de parasitología,departamento de biología celular y parasitología,universitat de valència,burjassot (valencia), Spain, department of clinical microbiology/clinical immunology,umeå university,umeå, Sweden, department of environmental health sciences,university medical center freiburg,freiburg, Germany, department of clinical chemistry,academic medical center,amsterdam, Netherlands, department of biochemistry and cell biology,faculty of veterinary medicine,utrecht university,utrecht, Netherlands, institute of bioinformatics,bangalore,india,mckusick-nathans institute of genetic medicine,johns hopkins university school of medicine,baltimore,md,united states,department of biological chemistry,johns hopkins university school of medicine,baltimore,md,united states,department of oncology and pathology,johns hopkins university school of medicine,baltimore,md, United States, mayo clinic,jacksonville,fl, United States, department of internal medicine,division of pulmonary,allergy,critical care and sleep medicine,davis heart and lung research institute,the ohio state university,columbus,oh, United States, center for brain repair and wellcome trust-mrc stem cell institute,department of clinical neurosciences,university of cambridge,cambridge, United Kingdom, institute of bioinformatics,bangalore, India, systems and cell biology of neurodegeneration,division of psychiatry research,university of zurich,zurich, Switzerland, institut curie,paris, France, cancer researaud,toulouse, France, department of chemistry,department of biochemistry and molecular biology,michigan state university,east lansing,mi, United States, servicio de inmunologia,hospital de la princesa,universidad autonoma madrid,madrid, Spain, laboratory of clinical chemistry and haematology,university medical center utrecht,utrecht, Netherlands, department of biosciences,division of biochemistry and biotechnology,university of helsinki, Finland, institute for biotechnology,university of aalborg, Denmark, department of biochemistry and cell biology,faculty of veterinary medicine and institute of biomembranes,utrecht university,utrecht, Netherlands, department of obstetrics,gynecology and women's health and james graham brown cancer center,university of louisville school of medicine,louisville,ky, United States, institut curie centre de recherche,paris,france,inserm u932,paris, France, department of rheumatology and inflammation research,sahlgrenska academy,university of gothenburg,gothenburg, Sweden, department of nephrology and hypertension,university medical center utrecht,utrecht, Netherlands, cardiovascular proteomics laboratory,centro nacional de investigaciones cardiovasculares (cnic),madrid, Spain, umr 5235 cnrs-university montpellier ii,montpellier, Finland, department of biochemistry and cell biology,faculty of veterinary medicine,life sciences,utrecht university,utrecht, Netherlands, unidad de investigación,hospital santa cristina,instituto de investigación sanitaria princesa,madrid, Spain, department of tumor cell biology,university hospital of surgery,heidelberg, Germany, department of biochemistry,la trobe institute for molecular science,la trobe university,melbourne,vic, Australia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|