simulation of some plasmonic biosensors for detection of hemoglobin concentration in human blood

Three recently published plasmonic biosensors based on a birefringent solid-core or a partial-solid-core microstructured optical fiber are simulated for detection of hemoglobin concentration in human blood. for a larger value of the number of holes n h but for the same value of the gold radius, the resonance spectral width and the difference between maximal amplitude sensitivity and resonant wavelengths are decreased, when the refractive index of the analyte is n a = 1.357. also, the loss and maximum of the amplitude sensitivity are increased in the same conditions. at the resonant wavelength λ = 0.6496 μm for the devices with n h = 14, 17, and 35 holes and n a = 1.357, the hemoglobin concentration is close to the mean value (157.5 g/l) of a man.