Clinical and histopathological findings of renal dysplasia in a miniature poodle dog

An 18-month-old,spayed female,miniature poodle dog was presented for preoperative evaluation of severe azotemia prior to surgical correction of bilateral medial patellar luxation. on physical examination,the dog appeared emaciated and less than 5% dehydrated. results of hematological analyses indicated leukopenia,azotemia,and hypercalcemia. additionally,urinalysis revealed proteinuria and low specific gravity compatible with chronic kidney disease (ckd). ultrasonography showed bilaterally small irregular kidneys. to make a definitive diagnosis,renal biopsy was performed under the guidance of ultrasound. histopathology revealed a high percentage of fetal glomeruli,which was consistent with congenital renal dysplasia. this case describes clinical and histopathological features of congenital renal dysplasia diagnosed by percutaneous renal biopsy. © 2015 pvj.