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Subcutaneous Leiomyosarcoma in a Smad3+/- Mouse
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نویسنده
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Kim Sang-Hyeob ,Ji Ae-Ri ,Park Jin-Kyu ,Kim Ah-Young ,Lee Eun-Mi ,Lee Eun-Joo ,Min Chang-Woo ,Kang Kyung-Ku ,Lee Myeong-Mi ,Sung Soo-Eun ,Hwang Meeyul ,Kwak Dong-Mi ,Kim Tae-Hwan ,Jeong Kyu-Shik
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منبع
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pakistan veterinary journal - 2014 - دوره : 34 - شماره : 3 - صفحه:420 -422
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چکیده
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Subcutaneous leiomyosarcoma is a malignant tumor that originates from smooth muscles in the skin. herein, we report a case of subcutaneous leiomyosarcoma that occurred in the ear pinna of a 19-month-old male smad3+/- mouse. on gross examination, the mass extended to the whole ear auricle and obscured the ear opening. the tumor was approximately 10x10 mm in size, ill-circumscribed, and firm with superficial hemorrhage. the cut surface of the mass was grayish-white and solid with focal necrosis and hemorrhage. histologically, spindle tumor cells with cigar-like nuclei and plump cells with round nuclei formed broad interlacing fascicles. additionally, the tumor cells invaded adjacent muscles. immunohistochemically, the tumor sections had positive reactions for desmine and a-sma and were partially positive for vimentin while negative for s-100 and myogenin. based on the results of the examination, we diagnosed this case as subcutaneous leiomyosarcoma.
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کلیدواژه
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Ear auricle ,Leiomyosarcoma ,Smad3+/- mouse ,Subcutaneous
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آدرس
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Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, South Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, South Korea, Kyungpook National University, College of Veterinary Medicine, Department of Pathology, Korea
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Authors
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