Supplementation of whole wheat diet on lipid profile in hypertensive females of various ethnic groups in Balochistan

The effects of supplemented whole wheat diet consumption for 4 weeks on body mass index (bmi),systolic and diastolic blood pressure,total cholesterol,low density lipoprotein cholesterol,high density lipoprotein cholesterol and triglycerides in sera were studied in hypertensive female subjects of 4 major ethnic groups i.e.,pathan,baloch,hazara,and punjabi in quetta region. two groups each of 32 hypertensive female subjects and comprising 8 subjects from each ethnic group were chosen. the control subjects used the conventionally available refined carbohydrates in meals and the treated group consumed 50g wheat cereals in breakfast and whole wheat chapattis in lunch and dinner. twelve hours fasting blood sample was taken from control and treated subjects a day after the completion of experiment duration. the whole grain diet subjects' bmi was insignificantly lower in all ethnic groups compare to their respective controls. lower systolic blood pressure was noticed in all ethnic groups; however,significantly in punjabi group only; and diastolic blood pressure was lower significantly in baloch,pathan and punjabi groups. total cholesterol was lower significantly in pathan,hazara and punjabi groups. significantly lower concentration of low density lipoprotein cholesterol was observed in baloch,pathan and punjabi groups. high density lipoprotein cholesterol and triglycerides were remarkably and significantly lower in treated volunteers of all the ethnic groups compared to their corresponding controls. in general there are matching responses of ameliorating lipid profile among the various ethnic groups; however,the variations observed are likely of nutrigenomic impact. © 2012 zoological society of pakistan.