A novel SNP of LXRa gene associated with meat quality traits in Cherry Valley Ducks

Liver x receptor alpha (lxra) is a nuclear receptor that play a crucial role in regulating the expression of genes involve in lipid metabolism. the aims of this study were to detect the polymorphisms of lxra gene and investigate their associations with cherry valley duck meat quality traits (n=450). a novel mutation 277c>g was first identified in exon 2 of lxra gene,which resulted in three genotypes of cc,cg and gg. c allele frequencies and polymorphism information content (pic) were 0.6200 and 0.3602,respectively. chi-square test indicated that genotypes distribution were in accord with hardy weinberg equilibrium (p>0.05). least square analysis showed that the birds with genotype cc had significant lower than genotype cg and genotype gg for polyunsaturated fatty acid (pufa) and essential fatty acid (efa) (p<0.05). the research suggested that the 277c>g mutation of duck lxra gene may be have significant effect on duck fatty acid composition,and g allele may be advantage for improving duck's pufa and efa. copyright 2014 zoological society of pakistan.