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Bioinformatic analyses of CCCH-Zinc finger family in zebrafish (Danio rerio)
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نویسنده
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shui y. ,xu z.-h. ,zhou x.
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منبع
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pakistan journal of zoology - 2014 - دوره : 46 - شماره : 4 - صفحه:989 -995
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چکیده
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Ccch-type zinc finger (zf) proteins are rna-binding proteins with regulatory functions at all stages of mrna metabolism. in this study,a genome-wide survey of ccch zf genes in zebrafish was performed for the first time. a total of 51 ccch genes were identified,but most have not been previously characterized. ccch motifs and other functional domains in the ccch protein family were classified and analyzed. phylogenetic and alignment analyses revealed that the zebrafish ccch family could be divided into seven groups. unlike in mammals,ccch proteins with six ccch motifs were not found in zebrafish. the fraction of ccch motifs with c-x7-8-c-x5-cx3- h type (63.5%) was smaller than that found in mouse ccch proteins (79%). copyright 2014 zoological society of pakistan.
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کلیدواژه
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CCCH motif; RNA-binding protein (RBP); Transcriptional regulation; Zebrafish
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آدرس
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key laboratory of freshwater fisheries and germplasm resources utilization,ministry of agriculture,chinese academy of fishery sciences, China, key laboratory of freshwater fisheries and germplasm resources utilization,ministry of agriculture,chinese academy of fishery sciences, China, key laboratory of freshwater fisheries and germplasm resources utilization,ministry of agriculture,chinese academy of fishery sciences,wuxi 214081,china,wuxi fishery college,nanjing agricultural university, China
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Authors
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