QTL for short-duration vigorous swimming movements in common carp (Cyprinus carpio L.) based on LDH activity

Lactate dehydrogenase (ldh) enzyme activities in muscle was significantly related with burst swimming speed and endurance swimming capacity in a variety of fish. quantitative trait loci (qtls) associated with ldh were analyzed based on f1 family crossed by hebao and heilongjiang carp. a total of seven qtls (qldh1,qldh6,qldh7,qldh21 qldh22,qldh45a and qldh45b) were detected on six linkage groups (lg1,lg6,lg7,lg21,lg22,lg45),and the explained variances of ldh activity by these qtls was more than 36%. confidence intervals ranged from 2.0 to 10 cm in the present study. to increase the intensity of qtl mapping,four new microsatellite markers (cafs02457,cafs02458,cafs02460,and cafs02461) were developed from common carp genomic fragments. intensity of candidate qtl intervals was increased (by > 5 cm) in four of the seven qtls. the pvalue of qldh7 was 0.0007 analyzed by an anova and explained 42.0% of the variance suggesting this qtl maybe a major qtl. copyright 2014 zoological society of pakistan.