Evaluation of commonly used anthelmintics resistance against nematodes infection in different breeds of sheep in Balochistan

In present study,four sheep breeds (i.e.,balochi,rakhshani,karakul and cross) were evaluated for resistance with three anthelmintics (oxfendazole. levamisole and ivermectin) against nematodes (haemonchus,trichostrongylus,nematodirus and ostertagia) between april 2011 to march 2012 at maslakh sheep farm,pishin district,balochistan. the overall results showed that there was reduction of epg between 95% to 99% indicating the susceptibility of these anthelmintics against nematodes in the study area. the results of egg hatch test showed lc 50 less than 0.1μg/ml of oxfendazole. this indicated that no resistance was found in eggs hatching to oxfendazole. in addition,the egg hatch test also confirmed the result of faecal egg count reduction test. the qualitative examination of faecal samples after coproculture revealed four gastrointestinal nematode genera,haemonchus contortus,trichostrongylus,nematodirus and ostertagia. copyright 2015 zoological society of pakistan.