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Genetic and clinical features of triploid fetus: A case report in han chinese population
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نویسنده
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zhu j. ,liu h. ,wang y. ,khan m.r. ,bukhari i. ,wang b.
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منبع
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pakistan journal of zoology - 2015 - دوره : 47 - شماره : 2 - صفحه:595 -598
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چکیده
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Triploidy is characterized by the presence of an additional set of chromosome in organisms. it has been proved lethal for humans' fetus and causing abortion at last trimester of pregnancy. some of the triploidy neonates can survive up to several weeks with several physical and mental abnormalities. in current study we enrolled a 27-year-old pregnant woman for genetic counseling with a suspect of edward's syndrome (trisomy 18) at her gestation period of 16 weeks,gtg-banded metaphase analysis revealed a karyotype of 69 xxx. microsatellite based genotyping of fetus and parents revealed that triploidy is initiated during meiosis-i and inherited from mother. therefore,we suggest that the diagnosis of triploidy should be performed at early stage of gestation to avoid the complication at late stages of pregnancy. copyright © 2015 zoological society of pakistan.
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کلیدواژه
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Diandric Triploidy; Digynic Triploidy; Fetal diagnosis; Prenatal diagnosis; Triploidy 69 XXX
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آدرس
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maternal and child health clinical college,anhui medical university,maternity and child health hospital of anhui province,hefei,china,department of laboratory medicine,affiliated provincial hospital of anhui medical university, China, maternal and child health clinical college,anhui medical university,maternity and child health hospital of anhui province, China, maternal and child health clinical college,anhui medical university,maternity and child health hospital of anhui province, China, school of life sciences,university of science and technology of china, China, school of life sciences,university of science and technology of china, China, department of laboratory medicine,affiliated provincial hospital of anhui medical university, China
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Authors
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