Heavy metals induced oxidative stress in multi-metal tolerant yeast,Candida sp. PS33 and its capability to uptake heavy metals from wastewater

Metal-resistant yeast strain,candida sp. ps33,isolated from industrial wastewater showed tolerance to pb (upto 35 mm),as (upto 29 mm),cu (upto 23 mm),cd (upto 11 mm) and cr (upto 8 mm). exposure to heavy metals at 0.1 mm for 2 days showed a remarkable increase in glutathione (gsh) level after as and pb treatment in contrast to cd,cr and cu exposure. gsh: gssg ratio declined after as,pb and cr treatment,whereas non-protein thiol levels were higher after cd and as treatment followed by those of pb,cr and cu treatment. candida sp. ps33 was able to remove 78% (cd),70% (as),82% (cu),65% (cr) and 87% (pb) from the medium after 8 days of incubation. this multi-resistant yeast can be used efficiently for the removal of toxic metals from the wastewater. copyright 2017 zoological society of pakistan.