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Synthesis,Spectral investigation (1H,13C) and Anti-microbial Screening of benzophenone imines
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نویسنده
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khosa m.k. ,jamal m.a. ,saif m.j. ,muneer m. ,ur-rehman f. ,farman m. ,shoaib h.m. ,shahid m. ,hameed s.
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منبع
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pakistan journal of pharmaceutical sciences - 2015 - دوره : 28 - شماره : 6 - صفحه:2167 -2171
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چکیده
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New series of benzophenone imines with general formula ph2-c=nr; r = benzyl,4-fluorobenzyl,naphthyl,phenyl,4-nitrophenyl were synthesized by condensation of dichlorodiphenylmethane and different aromatic primary amines (1:1) those imines were characterized by different physiochemical and spectroscopic techniques like melting point,elemental analysis,ft-ir,multinuclear nmr (1h,13c). after characterization,imines were subjected to antimicrobial activities. all compounds showed promising activity against different bacterial strains like escherichia coli,bacillussubtilis,pasturellam ultocida and staphylococcus aureus as well as fungal strains like alternata alternaria,ganoderma lucidium,penicillium notatum and trichoderma harzianum using amoxicillin and flucanazole as a standard drugs respectively.
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کلیدواژه
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Amoxicillin; Flucanazole; Imines; Schiff base
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آدرس
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department of chemistry,government college university, Pakistan, department of chemistry,government college university, Pakistan, department of applied chemistry,government college university, Pakistan, department of chemistry,government college university, Pakistan, department of applied chemistry,government college university, Pakistan, department of chemistry,quaid-e-azam university, Pakistan, department of chemistry,government college university, Pakistan, department of chemistry and biochemistry,university of agricultural, Pakistan, department of chemistry,government college university, Pakistan
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Authors
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