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   Synthesis,antioxidant and anti-microbial properties of two organoselenium compounds  
   
نویسنده talas z.s. ,gok y. ,ozdemir i. ,ates b. ,gunal s. ,yilmaz i.
منبع pakistan journal of pharmaceutical sciences - 2015 - دوره : 28 - شماره : 2 - صفحه:611 -616
چکیده    The aim of this study is synthesis of two different series of organoselenium compounds and available in vitro antioxidant and antimicrobial properties of these synthetic compounds. the synthetic compounds were identified by 1hnmr (300 mhz),13c-nmr (75.5 mhz),ft-ir spectroscopic techniques and micro analysis. antioxidant properties of two synthetic organoselenium compounds were determined by 1,1- diphenyl-2-picrylhydrazyl (dpph) radical method,reducing power assay and β-carotene bleaching method as in vitro. antimicrobial effects of samples were assessed by the agar dilution procedure and using gram positive and gram-negative bacteria and yeast strains. although 1,3-di-pmethoxybenzylpyrimidine- 2-selenone showed better antiradical activity in dpph test and higher protective activity on β- carotene,1-isopropyl-3-methylbenzimidazole-2-selenone was found to be better in reducing power and antimicrobial activity.
کلیدواژه Antimicrobial activity; Antioxidant activity; Synthetic organoselenium compounds
آدرس department of biology,faculty of arts and science,nigde university, Turkey, department of chemistry,faculty of arts and sciences,inonu university, Turkey, department of chemistry,faculty of arts and sciences,inonu university, Turkey, department of chemistry,faculty of arts and sciences,inonu university, Turkey, department of microbiology,faculty of medicine,inonu university, Turkey, department of chemistry,faculty of arts and sciences,inonu university, Turkey
 
     
   
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