Distribution and drug resistance profile of methicillin-resistant Staphylococcus aureus after orthopaedic surgery

This paper is aimed to comprehend clinical distribution and drug-resistance situation of methicillin-resistant staphylococcus aureus. this study applied automatic microbe instrument microscan w/a 96 for strain identification and drug susceptibility screening on the isolated strains. it was found that 312 mrsa strains were isolated in three years,which account for 58.1% of staphylococcus aureus. mrsa were mainly focused in wound secretion,purulent sputum and prostatic fluid and a few of them were isolated from blood specimens; endemic area distribution was mainly located in intensive care unit,neurosurgery,respiratory department,dermatology,orthopaedic burns and orthopaedics. mrsa strains showed high drug resistance of 82.37%~100% to most of the antibiotics including vancomycin,cotrimoxazole and rifampicin. strain was 100% resistance towards ampicillin,amoxicillin/acid,cefalotin,cefazolin,tienam,benzylpenicillin,penicillin and tetracycline and 90% strains resisted clindamycin,cefotaxime,clarithromycin and gentamicin.