The expression and significance of XIAP and C-jun on Condyloma acuminatum

Objective of the study was to investigate the expression and significance of xiap and c-jun in condyloma acuminatum. the immunohistochemistry sabc method was adopted to detect the expression of xiap and c-jun in condyloma acuminatum. the positive expression rate of xiap and c-jun in condyloma acuminatum was 80% (32/40) and 90% (36/40) separately and the intensity of expression was usually ++ ~ +++. while in control group,the positive expression rate of xiap and c-jun was 27.8% (5/18) and 16.7 % (3/18) separately,and the intensity of expression was - ~ ++. there was statistical significance of the positive expression rate and the expression intensity of xiap and c-jun between the two groups (p<0.05). besides,the positive correlation existed between expression of xiap and c-jun (r=0.306 p<0.01). the over-expression of xiap and c-jun in condyloma acuminatum may be associated with the growth of condyloma acuminatum.