Antibacterial, Anti-fungal and Phytotoxic activities of Ferula narthex Boiss.

Crude methanolic extract of roots, aerial parts and its subsequent fractions of ferula narthex boiss were tested for antibacterial, anti-fungal and phytotoxic activities. crude methanolic extract of roots and its fractions showed significant antibacterial effect against p.aeruginosa (86.95%, 73.91, 69.59, 78.26 & 73.91%) represented by percent inhibition except ethyl acetate (etoac) fraction. the etoac fraction of roots and aerial parts showed significant activity against e. coli (80%), s. typhi (81.2 & 81.25%) and s. pneumoniae (80%). the n-hexane, chloroform and aqueous fractions of aerial parts showed significant activity against p. aeruginosa (78.26, 69.56 & 73.91%). following fungal strains (t. longifusus, c. albicans, a. flavus, m. canis, f. solani, c. glabrata) were also used for anti-fungal activity. among tested samples only crude methanol extract of roots, n-hexane and chloroform fraction showed moderate antifungal activity against m. canis (40, 35 & 30%) represented by percent inhibition. the remaining fractions showed no effect on tested fungi. different oils fractions were also tested against above fungal strains. fraction i, ii & v showed mild to moderate activity against m. canis (40, 40 & 25%). phytotoxic effect of tested samples of roots, aerial part and its fractions showed concentration dependent growth inhibition. maximum phytotoxic effect was noted for n-hexane and aqueous fraction (50% growth inhibition). the remaining tested samples showed mild effect on growth of lemna minor plant.