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Anti-glycationand Anti-oxidation properties of Capsicum frutescens and Curcuma longa fruits: Possible role in prevention of diabetic complication
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نویسنده
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Khan Ibrar ,Ahmad Haroon ,Ahmad Bashir
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منبع
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pakistan journal of pharmaceutical sciences - 2014 - دوره : 27 - شماره : 5 - صفحه:1359 -1362
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چکیده
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The accumulation of advanced glycationend products (age’s) in the body, due to the non-enzymatic glycation of proteins is associated with several pathological conditions like aging and diabetes mellitus. hence a plant having anti-glycation and anti-oxidation potentials may serve as therapeutic agent for diabetic complications and aging. in this study the anti-glycation and anti-oxidation properties of crude methanolic extracts of fruits of capsicum frutescens and curcuma longa were investigated. among the two c. frutescens had more anti-glycation ability with a minimum inhibitory concentration (mic50) of 90μg/mlas compared to 324μg/ml mic50 of c. longa. curcuma longa had the more anti-oxidation potential i.e. 35.01, 30.83 and 28.08% at 0.5mg, 0.25mg and 0.125mg respectively.
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کلیدواژه
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AGE’s ,Anti-glycation ,Anti-oxidation ,Capsicum frutescens ,Curcuma longa.
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آدرس
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University of Peshawar, Centre of Biotechnology and Microbiology, Pakistan, University of Peshawar, Centre of Biotechnology and Microbiology, Pakistan, University of Peshawar, Centre for Biotechnology and Microbiology, Pakistan
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Authors
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