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   Anti-glycationand Anti-oxidation properties of Capsicum frutescens and Curcuma longa fruits: Possible role in prevention of diabetic complication  
   
نویسنده Khan Ibrar ,Ahmad Haroon ,Ahmad Bashir
منبع pakistan journal of pharmaceutical sciences - 2014 - دوره : 27 - شماره : 5 - صفحه:1359 -1362
چکیده    The accumulation of advanced glycationend products (age’s) in the body, due to the non-enzymatic glycation of proteins is associated with several pathological conditions like aging and diabetes mellitus. hence a plant having anti-glycation and anti-oxidation potentials may serve as therapeutic agent for diabetic complications and aging. in this study the anti-glycation and anti-oxidation properties of crude methanolic extracts of fruits of capsicum frutescens and curcuma longa were investigated. among the two c. frutescens had more anti-glycation ability with a minimum inhibitory concentration (mic50) of 90μg/mlas compared to 324μg/ml mic50 of c. longa. curcuma longa had the more anti-oxidation potential i.e. 35.01, 30.83 and 28.08% at 0.5mg, 0.25mg and 0.125mg respectively.
کلیدواژه AGE’s ,Anti-glycation ,Anti-oxidation ,Capsicum frutescens ,Curcuma longa.
آدرس University of Peshawar, Centre of Biotechnology and Microbiology, Pakistan, University of Peshawar, Centre of Biotechnology and Microbiology, Pakistan, University of Peshawar, Centre for Biotechnology and Microbiology, Pakistan
 
     
   
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