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Antimicrobial and toxicological studies of Ochthochloa compressa plant
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نویسنده
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Ahmad Saeed ,Bashir Muhammad Tayyab ,Khaliq Farhan Hameed ,Abdul Mannan ,Mukhtar Muhammad Fahad
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منبع
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pakistan journal of pharmaceutical sciences - 2014 - دوره : 27 - شماره : 5 - صفحه:1209 -1213
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چکیده
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The present study demonstrates the biological activity of ochthochloa compressa, since extensive literature survey has shown no documented biological activity of this plant. ethanolic extract of whole plant was prepared and evaporated under reduced pressure by rota vapor. the crude extract was further fractionated into n- hexane, dichloromethane, ethyl acetate and n-butanol soluble fractions. these fractions were screened for antifungal, phytotoxic, cytotoxic and antibacterial activities. dichloromethane soluble fraction showed significant phytotoxicity whereas nhexane, ethyl acetate, and n-butanol soluble fractions showed non-significant phytotoxicity. similarly, ethyl acetate soluble fraction was the only fraction, which showed significant cytotoxic activity. there was no antibacterial but moderate antifungal activity was shown by these fractions against selected strains of bacteria and fungi. this is the first report on the biological activity of o. compressa.
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کلیدواژه
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Ochthochloa compressa ,phytotoxicity ,biological activity
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آدرس
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Islamic University of Bahawalpur, Faculty of Pharmacy &Alternative Medicine, Pakistan, Islamia University of Bahawalpur, Faculty of Pharmacy &Alternative Medicine, Pakistan, Islamia University of Bahawalpur, Faculty of Pharmacy &Alternative Medicine, Pakistan, Islamia University of Bahawalpur, Faculty of Pharmacy &Alternative Medicine, Pakistan, Islamia University of Bahawalpur, Faculty of Pharmacy &Alternative Medicine, Pakistan
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Authors
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Abdul Mannan
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