>
Fa   |   Ar   |   En
   Preliminary phytochemical screening, antimicrobial and antioxidant activities of Euphorbia milli  
   
نویسنده Abdur Rauf ,Khan Ajmal ,Nizam Uddin ,Akram Muhammad ,Arfan Mohammad ,Ghias Uddin ,Qaisar Muhammad
منبع pakistan journal of pharmaceutical sciences - 2014 - دوره : 27 - شماره : 4 - صفحه:947 -951
چکیده    Euphorbia milii is a pakistani herb used for various infectious diseases. in this study we have carried out phytochemical, antibacterial and antioxidant investigation of different extracts/fractions. phytochemical studies showed the presence of cardiac glycosides, steroids/phytosterols, anthocyanin, proteins, terpenoids, flavonoids and tannins. susceptibility testing by well diffusion assay of its chloroform and methanol fractions revealed good antimicrobial activity against klebsiella pneumonia and staph epidermis. ethyl acetate fraction of roots also exhibited considerable antimicrobial activity against most of tested pathogens. various fractions (hexane, chloroform, methanol and water) of e. milii were screen for their antioxidant potential using dpph radical scavenging assay at different concentrations among these, chloroform fraction exhibited good scavenging activity. the ir spectroscopy of the various extracts/fractions indicated the presence of oh, saturated ch stretching, c=c, c=o, no2, c-n, ar-o, c-o- and r-ostretching respectively. the findings provide helpful evidence for the use of e. milii in traditional medicines.
کلیدواژه Euphorbia milli ,antimicrobial activity ,DPPH radical scavenging assay ,IR spectroscopy.
آدرس University of Peshawar, Institute of Chemical Sciences, Center of Phytomedicine and Medicinal, Organic Chemistry Laboratory, Pakistan, University of Karachi, HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, Pakistan, University of Karachi, Center of Excellence in Marine Biology, Pakistan. Batterje Medical College for Science & Technology, Saudi Arabia, University of Peshawar, Institute of Chemical Sciences, Center of Phytomedicine and Medicinal, Organic Chemistry Laboratory, Pakistan. PCSIR Laboratories Complex, Pakistan, University of Peshawar, Institute of Chemical Sciences, Center of Phytomedicine and Medicinal, Organic Chemistry Laboratory, Pakistan, University of Peshawar, Institute of Chemical Sciences, Center of Phytomedicine and Medicinal, Organic Chemistry Laboratory, Pakistan, PCSIR Laboratories Complex, Pakistan
 
     
   
Authors Abdur Rauf ,Nizam Uddin ,Ghias Uddin
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved