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Antioxidant and antibacterial activities of Hibiscus Rosa-sinensis Linn flower extracts
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نویسنده
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Khan Zulfiqar Ali ,Naqvi Ali Raza ,Mukhtar Ammara ,Hussain Zaib ,Shahzad Sohail Anjum ,Mansha Asim ,Ahmad Matloob ,Zahoor Ameer Fawad ,Bukhari Iftikhar Hussain ,Janjua Muhammad Ramazan Saeed Ashraf ,Mahmood Nasir ,Yar Muhammad
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منبع
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pakistan journal of pharmaceutical sciences - 2014 - دوره : 27 - شماره : 3 - صفحه:469 -474
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چکیده
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Antioxidant and antibacterial potential of different solvent extracts of locally grown hibiscus rosa-sinensis linn was evaluated. the antioxidant activity was assessed by estimation of total flavonoids contents, total phenolic contents, dpph free radical scavenging activity and percentage inhibition of linoleic acid oxidation capacity. agar disc diffusion method was used to assess antibacterial potential of crude extract of h. rosa-sinensis. the yield of the crude extracts (23.21±3.67 and 18.36±2.98% in 80% methanol and ethanol solvents was calculated, respectively. methanol and ethanol extract of h. rosa-sinensis showed total phenolics 61.45±3.23 and 59.31±4.31 mg/100g as gallic acid equivalent,total flavonoids 53.28±1.93 and 32.25±1.21 mg/100g as catechine equivalent, dpph free radical scavenging activity 75.46±4.67 and 64.98±2.11% and inhibition of linoleic acid oxidation potential 75.8±3.22 and 61.6±2.01% respectively, was measured. antibacterial study against three human pathogens such as staphlococus sp. bacillus sp. and escherichia coli showed growth inhibitory effect in the range of 12.75±1.17 to 16.75±2.10 mm. these results showed h. rosasinensis indigenous to kallar kahar and its allied areas bear promising medicinal values and could be used for developing herbal medicines to target oxidative stress and infectious diseases.
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کلیدواژه
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H. rosa ,antibacterial activity ,Kallar Kahar ,antioxidant ,diabetes
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آدرس
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Government College University, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, University of the Punjab, Institute of Chemistry, Pakistan, COMSATS institute of information technology, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, Government College University, Department of Chemistry, Pakistan, University of Sargodha, Department of Chemistry, Pakistan, University of Health Sciences, Department of Allied Sciences and Chemical Pathology, Pakistan, COMSATS Institute of Information Technology, Interdisciplinary Research Center in Biomedical Materials, Pakistan
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Authors
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