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ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITIES OF ETHANOLIC ROOT EXTRACT OF CROTON ZAMBESICUS
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نویسنده
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OKOKON JUDE E ,NWAFOR PAUL A
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منبع
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pakistan journal of pharmaceutical sciences - 2010 - دوره : 23 - شماره : 4 - صفحه:385 -392
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چکیده
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The ethanolic root extract of c. zambesicus (27-81mg/kg) was evaluated for antiiflammatory, analgesic and antipyretic properties in mice. the extract (27-81mg/kg) demonstrated a weak antiinflammatory activity. however, a significant (p<0.01-0.001) analgesic and antipyretic activities were observed in all the experimental models tested. the extract may be exerting its effects through central mechanisms. these findings confirms its ethnomedical use in the treatment of malarial-associated symptoms.
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کلیدواژه
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Antiinflammatory ,analgesic ,antipyretic ,Croton zambesicus
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آدرس
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University of Uyo, Department of Pharmacology and Toxicology, Nigeria, University of Uyo, Department of Pharmacology and Toxicology, Nigeria
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Authors
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