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ANALYSIS OF SOME BIOCHEMICAL AND HAEMATOLOGICAL PARAMETERS FOR MUCUNA PRURIENS (DC) SEED POWDER IN MALE RATS
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نویسنده
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CHUKWUDI NDUKWE HENRY ,SIMEON OMALE ,CHINYERE AGUIYI JOHN
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منبع
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pakistan journal of pharmaceutical sciences - 2011 - دوره : 24 - شماره : 4 - صفحه:523 -526
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چکیده
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The biochemical and haematological effects of the seed powder of mucuna pruriens in male rats were evaluated to establish some biological properties of this potential biopesticide currently undergoing investigation. the result showed that mucuna pruriens seed extract produced a significant (p<0.05) increase in white blood cell (wbc) count, as well as in bilirubin concentrations, alkaline phosphatase (alp), protein and creatinine levels measured. alanine aminotransferase (alt) and aspartate aminotransferase (ast) were significantly reduced (p<0.05) in comparison with the experimental control. pcv, hb, albumin level and wbc differential counts gave no significant difference between treated and control groups. the results revealed metabolic imbalance in the rats which suggests a mild cholestasis effect of the extract.
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کلیدواژه
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Mucuna pruriens ,alanine aminotransferase ,aspartate aminotransferase.
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آدرس
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University of Jos, Faculty of Pharmaceutical Sciences, Department of Clinical Pharmacy, Nigeria, University of Jos, Faculty of Pharmaceutical Sciences, Department of Clinical Pharmacy, Nigeria, University of Jos, Faculty of Pharmaceutical Sciences, Department of Pharmacology, Nigeria
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Authors
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