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FORMULATION AND EVALUATION OF CETIRIZINE DIHYDROCHLORIDE ORODISPERSIBLE TABLET
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نویسنده
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SUBRAMANIAN S ,SANKAR V ,MANAKADAN ASHA ASOKAN ,ISMAIL SAREENA ,ANDHUVAN G
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منبع
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pakistan journal of pharmaceutical sciences - 2010 - دوره : 23 - شماره : 2 - صفحه:232 -235
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چکیده
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Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. the flow property of granules was found to be good for the formulation cz2 (1:1:3). the hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. disintegration time was found to be rapid in formulation cz2 (1:1:3).the in vitro dissolution time was found to be 100% in 11 minutes for the formulation cz2 (1:1:3).
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کلیدواژه
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Cetirizine orodispersible tablets ,HPLC method ,hausner ratio ,wetting time
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آدرس
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PSG College of Pharmacy, Department of Pharmaceutics, India, PSG College of Pharmacy, Department of Pharmaceutics, India, Grace College of Pharmacy, Department of Pharmaceutics, India, Grace College of Pharmacy, Department of Pharmaceutics, India, Karpagam Pharmacy College, Department of Pharmacy Practice, India
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Authors
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