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SYNTHESIS OF SOME NOVEL ANALOGUES OF 4-(1-PYRROLIDINYL) PIPERIDINE AND THEIR EFFECT ON PLASMA GLUCOSE LEVEL
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نویسنده
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MUSHTAQ NOUSHEEN ,SAIFY Z.S. ,AKHTAR SHAMIM ,ARIF MUHAMMAD ,HAIDER SAIDA ,SABA NAZISH
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منبع
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pakistan journal of pharmaceutical sciences - 2010 - دوره : 23 - شماره : 2 - صفحه:220 -223
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چکیده
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In the present study some compounds of 4-(1-pyrrolidinyl) piperidine (i) have been synthesized. structures of compounds were confirmed by using hnmr, ir, mass and uv spectrophotometer techniques. all the derivatives (ii, iii, iv and v) and the parent compound (i) at the dose of 100 mg/kg were evaluated for their effect on plasma glucose level. compound (ii) was the only derivative which showed effect on plasma glucose level.
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کلیدواژه
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Piperidine (I) ,plasma glucose level ,derivatives
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آدرس
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University of Karachi, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Pakistan, University of Karachi, HEJ Research Institute of Chemistry, Pakistan, University of Karachi, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Pakistan, University of Karachi, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Pakistan, University of Karachi, Department of Biochemistry, Pakistan, University of Karachi, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Pakistan
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Authors
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