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ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITY OF H. OFFICINALIS L. VAR. ANGUSTIFOLIUS, V. ODORATA, B. HYRCANA AND C. SPECIOSUM
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نویسنده
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EBRAHIMZADEH MOHAMMAD ALI ,NABAVI MOHAMMAD ,NABAVI FAZEL ,BAHRAMIAN FATEMEH ,BEKHRADNIA AHMAD REZA
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منبع
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pakistan journal of pharmaceutical sciences - 2010 - دوره : 23 - شماره : 1 - صفحه:29 -34
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چکیده
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Extracts of 4 medicinal and aromatic plants were investigated for their antioxidant potency employing six various established in vitro system: h. officinalis l. var. angustifolius aerial parts, c. speciosum flowers, v. odorata and b. hyrcana leaves.with regard to ic50 values (μg/ ml), the order in dpph radical-scavenging were cs (585.6) > ho (311) > vo (245.1) > and bh (113.1). effectiveness in reducing powers were high and in a descending order of ho > cs > bh > vo (at the concentrations of 25-800 μg/ ml). ic50 for fe^2+ chelating ability were 188, 750 and 980 μg/ ml for vo, cs and ho, respectively. bh extract has shown only 38% inhibition at 800 μg/ ml. the extracts showed weak nitric oxide-scavenging activity. all extracts exhibited very low and moderate concentration-dependent antioxidant activity in ftc methods. ic50 for scavenging of h2o2 were 169 for bh, 175 for cs, 640 for vo and 663 μg/ ml for ho. the content of total phenolic compounds and flavonoids were measured in plant extracts. the data obtained in the in vitro models clearly establish the antioxidant potency of all extracts.
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کلیدواژه
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Antioxidant activity ,DPPH ,H. officinalis ,C. speciosum ,V. odorata ,B. hyrcana
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آدرس
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mazandaran university of medical sciences, Pharmaceutical Sciences Research Center, School of Pharmacy, ایران, mazandaran university of medical sciences, Pharmaceutical Sciences Research Center, School of Pharmacy, ایران. university of mazandaran, Department of Biology, ایران, mazandaran university of medical sciences, Pharmaceutical Sciences Research Center, School of Pharmacy, ایران, mazandaran university of medical sciences, Student Research Committee, ایران, mazandaran university of medical sciences, Pharmaceutical Sciences Research Center, School of Pharmacy, ایران
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Authors
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